DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and Mars1

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_006241513.1	Gene:	Mars1 / 299851	RGDID:	1305321	Length:	910	Species:	Rattus norvegicus

Alignment Length:	388	Identity:	85/388 - (21%)
Similarity:	140/388 - (36%)	Gaps:	99/388 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 KVPAFETAEGQYLSESNAIA---YLLANEQLRGGKCPFVQAQV-QQWISFADNEIVPASCAWVFP 114
            |||..:...|.||..::||.   :||         |.:.|..: .||:.:...|:.|...|.::.
  Rat    47 KVPVLQLDSGNYLFSASAICRYFFLL---------CGWEQDDLTNQWLEWEATELQPVLSAALYC 102

  Fly   115 LLGILPQQKNSTAKQEAEAVLQQLNQKL--QDATFLAGERITLADIVVFSSLLHLYEYVLEPS-V 176
            |  ::..:|..........||..::..|  |:..||||:..:|||||::.:   ||..:.:|: :
  Rat   103 L--VVQGKKGEDVLGPLRRVLTHIDHSLSRQNCPFLAGDTESLADIVLWGA---LYPLLQDPAYL 162

  Fly   177 RSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTG---AAKPQQQAQQQKQ 238
            ....|.:..||.|:..|:.          |::|        ||...|..   |.:|..|.|.|.|
  Rat   163 PEELGALQSWFQTLSTQEP----------CQRA--------AETVLKQQGVLALRPYLQKQPQPQ 209

  Fly   239 EKKPKEKKEAPKKAAEPAEELDAA---DEALAAEPKSKDPFDALPKGTFNFDDFKRVYSNEDEAK 300
            ...|    |....:.||.||..|.   ::.:||....:...:.||.          :...:....
  Rat   210 PLPP----EGRAVSNEPEEEELATLSEEDIIAAVAAWEKGLENLPP----------LQPQQHPVL 260

  Fly   301 SIPYFFDKFDAENYSIWFGE----------YKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASV 355
            .:|               ||          |..|.......:.|.|...:|.|..::|:.....:
  Rat   261 PVP---------------GERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYL 310

  Fly   356 CLFGEDGNSTISGIWVWRGQDLAFTLSPD------WQIDYEVYDWKKL--DAKSEETKKLVTQ 410
            |...|.|.:|       ..:.:...|:|.      ..|..::|.|..:  |.....|..|.|:
  Rat   311 CGTDEYGTAT-------ETKAMEEGLTPQEICDKYHAIHVDIYRWFNISFDTFGRTTTPLQTK 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	10/27 (37%)
		GstA	5..187	CDD:223698	36/139 (26%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	30/122 (25%)
		EF1G	271..376	CDD:279041	16/114 (14%)
Mars1	XP_006241513.1	Thioredoxin_like	1..68	CDD:294274	8/20 (40%)
		GstA	<47..189	CDD:223698	44/173 (25%)
		GST_C_MetRS_N	77..179	CDD:198340	28/106 (26%)
		PRK12268	266..821	CDD:237029	20/108 (19%)
		MetRS_core	267..635	CDD:173907	20/107 (19%)
		Anticodon_Ia_Met	644..773	CDD:153411
		MetRS_RNA	855..899	CDD:238475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810