DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTE1

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_319969.1	Gene:	GSTE1 / 1280156	VectorBaseID:	AGAP009195	Length:	224	Species:	Anopheles gambiae

Alignment Length:	207	Identity:	56/207 - (27%)
Similarity:	94/207 - (45%)	Gaps:	22/207 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKGTLYTYPENFRAYKALIAAQYSGAQV-KVADNFKFGETNKSAEFLKKFPGGKVPAFETAEGQ 64
            |.|..|||...:.......:.|:..|.:: :...|...|| |.:.||||..|...:|..:. .|.
Mosquito     1 MPKPVLYTVHLSPPCRAVELTAKALGLELERKLVNLLAGE-NLTPEFLKLNPKHTIPVLDD-NGT 63

  Fly    65 YLSESNAIAYLLANEQLRG-GKCPFV------QAQVQQWISFADNEIVPASCAWVFPLLGILPQQ 122
            .:|||:||...|..:..:| ||....      ||:|.:.:.| ::.::.|...::..|  :...:
Mosquito    64 IISESHAIMIYLVRKYGQGEGKDALYPTDIVEQARVNEALHF-ESGVLFARLRFITEL--VFFAR 125

  Fly   123 KNSTAKQEAEAV---LQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVN 184
            |....:...|.|   .:.|...|| :.::||.|:|:||:...||:..:..::  |..||.|..|:
Mosquito   126 KPEIPEDRIEYVRTAYRLLEDSLQ-SDYVAGSRMTIADLSCISSVASMVGFI--PMERSEFPRVH 187

  Fly   185 RWFVTILNQKQV 196
            .|   |...||:
Mosquito   188 GW---IERMKQL 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	22/75 (29%)
		GstA	5..187	CDD:223698	50/192 (26%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	29/110 (26%)
		EF1G	271..376	CDD:279041
GSTE1	XP_319969.1	GST_N_Delta_Epsilon	4..76	CDD:239343	21/73 (29%)
		GstA	6..197	CDD:223698	54/202 (27%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	29/112 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810