DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTE4

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_319967.1	Gene:	GSTE4 / 1280154	VectorBaseID:	AGAP009193	Length:	225	Species:	Anopheles gambiae

Alignment Length:	176	Identity:	37/176 - (21%)
Similarity:	71/176 - (40%)	Gaps:	25/176 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 NFRAYKALIA---------AQYSGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEGQYLS 67
            |.:.|.|.::         |:..|.::.:.......:.:.:..|.|..|...:|..:. .|..:.
Mosquito     3 NIKLYTAKLSPPGRSVELTAKALGLELDIVPINLLAQEHLTEAFRKLNPQHTIPLIDD-NGTIVW 66

  Fly    68 ESNAI-AYLLANEQLRGGKCPF----VQ-AQVQQWISFADNEIVPASCAWVFPLLGI----LPQQ 122
            :|:|| .||::......|...:    || |:|...:.|....:......::.|:|..    .||:
Mosquito    67 DSHAINVYLVSKYGKPEGDSLYPSDVVQRAKVNAALHFDSGVLFARFRFYLEPILYYGATETPQE 131

  Fly   123 KNSTAKQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLY 168
            |.....:..|.    ||..|.| .::.|..:||||:...:|:..::
Mosquito   132 KIDNLYRAYEL----LNDTLVD-EYIVGNEMTLADLSCIASIASMH 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	15/76 (20%)
		GstA	5..187	CDD:223698	37/176 (21%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	20/84 (24%)
		EF1G	271..376	CDD:279041
GSTE4	XP_319967.1	GstA	4..211	CDD:223698	36/175 (21%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	14/73 (19%)
		GST_C_Delta_Epsilon	93..210	CDD:198287	21/85 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810