DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and AgaP_AGAP007891

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_317601.4	Gene:	AgaP_AGAP007891 / 1278067	VectorBaseID:	AGAP007891	Length:	977	Species:	Anopheles gambiae

Alignment Length:	418	Identity:	86/418 - (20%)
Similarity:	150/418 - (35%)	Gaps:	108/418 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYTYPENFRAYKALIAAQYSGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEG-QYLSES 69
            :||...|....|.||.|..:...|:|    |....|..|....|    .:|..:...| |..|..
Mosquito     3 IYTNTGNPFGLKLLICANLAKTNVEV----KHVTLNDPALGDMK----HLPILQLNSGVQLFSTD 59

  Fly    70 NAIAYLLANEQLRGGKCPFVQAQVQQWISFADNEIVPA---SCAWVFPLLGILPQQKNSTAKQEA 131
            .|..|||..:.  ..|.    .|..:|:.::...:.||   :.|        :..:.:...|...
Mosquito    60 VAAKYLLPGDD--ASKV----VQRDEWLEWSSKRLAPALTHNMA--------VGSRADPNTKPIL 110

  Fly   132 EAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQV 196
            ..:::.|:..|.::|||.|::|:.||:.|:|.|..  :..|:.:|.  ..||.||:..|....:|
Mosquito   111 NTLVKMLDDCLSNSTFLTGDKISSADVAVWSLLAP--DGTLKGAVN--IDNVLRWYRQITALPEV 171

  Fly   197 QAVVKDYKLCEKA---------------LVFDPKKYAEFQAKTGAAKPQQQAQQQKQEKKPKEKK 246
            |:.:....|.|.:               :|.:| :.|:|:.:..|......|     |...:|:.
Mosquito   172 QSALAALPLKELSFASLQHSNRFGGLHHIVLNP-EIADFEGELLADTSANIA-----ETVQREEI 230

  Fly   247 EAPKKAAEPAEELDAADEALAAEPK--SKDPF--DALPKGTFNFDDFKRVYSNEDEAKSIPYFFD 307
            ||.:.|....::....||.....||  .|:..  .|||            |.|     ::|:..:
Mosquito   231 EAARAAFGETDDRAVRDEPRIVLPKPGQKNNLITSALP------------YVN-----NVPHLGN 278

  Fly   308 KFDAENYSIWFGEYKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASVCLFGEDGNSTISGIWVW 372
                                   .:.|.|...:|.|..::  ..:.::.:.|.|...|.:
Mosquito   279 -----------------------IVGCVLSADIFARYSRL--CGYNTLYIGGTDEYGTAT----- 313

  Fly   373 RGQDLAFTLSPD------WQIDYEVYDW 394
            ..:.||..::|.      :.|...:|.|
Mosquito   314 ETKALAENMTPRQICDKYFDIHNSIYRW 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	21/73 (29%)
		GstA	5..187	CDD:223698	45/184 (24%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	29/121 (24%)
		EF1G	271..376	CDD:279041	15/108 (14%)
AgaP_AGAP007891	XP_317601.4	GstA	1..179	CDD:223698	49/201 (24%)
		GST_N_family	1..65	CDD:238319	18/69 (26%)
		GST_C_MetRS_N	67..168	CDD:198340	26/118 (22%)
		MetRS_core	260..633	CDD:173907	19/129 (15%)
		PRK12268	262..820	CDD:237029	19/127 (15%)
		Anticodon_Ia_Met	642..771	CDD:153411
		MetRS_RNA	843..887	CDD:238475
		MetRS_RNA	917..961	CDD:238475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910