DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTD10

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_313668.1	Gene:	GSTD10 / 1274530	VectorBaseID:	AGAP004383	Length:	211	Species:	Anopheles gambiae

Alignment Length:	202	Identity:	49/202 - (24%)
Similarity:	89/202 - (44%)	Gaps:	34/202 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KVADNFKFGETN----KSAEFLKKF-PGGKVPAFETAEGQYLSESNAIAYLLANEQLRGG----- 84
            |:...|...|.|    :..|.|:|| |...:|.| ..:|..:.||.|||..|..:...|.
Mosquito    21 KLGITFDLKEVNPHLPEVREQLRKFNPQHTIPTF-IEDGHVIWESYAIAIYLVEKYGNGDDALYP 84

  Fly    85 KCPFVQAQVQQWISFADNEIVPASCAWVFPLL--GILPQQKNSTAKQEAEAVLQQLNQKLQDATF 147
            :.|.|::.|.|.:.|.:..:..::..:|..:|  .:.|.::   .:|..:..|..|...:::..|
Mosquito    85 RDPKVRSVVNQRLFFDNGLMFKSAIEYVECILKKKLEPTEE---MQQRLKKALGLLESFVKERAF 146

  Fly   148 LAGERITLADIVVFSS--LLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDY-----KL 205
            :|.:.:|:|||.:.||  ||...:|.|     :.|..:..|...:..:      :.||     :|
Mosquito   147 VASDHLTIADICLLSSVTLLTGIKYDL-----ATFPGITAWVARVTGE------LPDYGEFHKEL 200

  Fly   206 CEKALVF 212
            .||::.:
Mosquito   201 YEKSMEY 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	18/53 (34%)
		GstA	5..187	CDD:223698	43/170 (25%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	27/127 (21%)
		EF1G	271..376	CDD:279041
GSTD10	XP_313668.1	GstA	1..186	CDD:223698	44/173 (25%)
		GST_N_Delta_Epsilon	1..73	CDD:239343	18/52 (35%)
		GST_C_Delta_Epsilon	88..200	CDD:198287	26/125 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810