DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTD12

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_313666.2	Gene:	GSTD12 / 1274528	VectorBaseID:	AGAP004380	Length:	211	Species:	Anopheles gambiae

Alignment Length:	156	Identity:	41/156 - (26%)
Similarity:	66/156 - (42%)	Gaps:	27/156 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 EFLKKF-PGGKVPAFETAEGQYLSESNAIAYLLANEQLRGGK------CPFVQAQVQQWISFADN 102
            |.|||. |...:|.. ...|..|.||.||...||.:......      |.  ::.|.|.:.|...
Mosquito    40 EVLKKVNPQHTIPTL-VDNGHILWESYAILIYLAEKYALDDSLYPKDVCE--RSIVHQRLFFDSG 101

  Fly   103 EIVPASCAWVFPLLGILPQQKNSTAKQEAEAVLQQ----LNQKLQDATFLAGERITLADIVVFSS 163
            .....:      |..:|...:|:....|..|.:::    :...|.|:.::||:::|:||..:|.|
Mosquito   102 MFQNTT------LQAVLSHLRNNPITDEHLAKVKRGVEIVEMYLTDSPYVAGQKLTIADFSIFVS 160

  Fly   164 L--LHLYEYVLEPSVRSAFGNVNRWF 187
            .  |.:.:|.|     :|:.||.|||
Mosquito   161 FCSLDMMKYDL-----TAYPNVQRWF 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	14/34 (41%)
		GstA	5..187	CDD:223698	39/154 (25%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	26/104 (25%)
		EF1G	271..376	CDD:279041
GSTD12	XP_313666.2	GstA	1..204	CDD:223698	41/156 (26%)
		GST_N_Delta_Epsilon	1..73	CDD:239343	13/33 (39%)
		GST_C_Delta_Epsilon	88..200	CDD:198287	26/107 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810