DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eEF1gamma and GSTD11

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_313665.4	Gene:	GSTD11 / 1274527	VectorBaseID:	AGAP004378	Length:	214	Species:	Anopheles gambiae

Alignment Length:	190	Identity:	49/190 - (25%)
Similarity:	80/190 - (42%)	Gaps:	18/190 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEGQY-LSESNAI-AYLLANEQLRGG---KCPF 88
            :|..|..| ||..| .||||..|...||..  .:..: |.||.|| .||........|   |.|.
Mosquito    28 LKEVDLLK-GEHLK-PEFLKINPQHTVPTL--VDNDFVLWESRAILTYLCEKYGKNDGLYPKDPK 88

  Fly    89 VQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNSTAKQEAEAVLQQLNQKLQDATFLAGERI 153
            .:|.|.|.:.|....:........:|:: :..::.|.....:.:..|:.|...|....|.||:::
Mosquito    89 KRAVVNQRLYFDMGTLYQRFSQAFYPVM-MEGKELNPELVVKLDEALEFLESFLDKTPFAAGDKL 152

  Fly   154 TLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLC-EKALVF 212
            |:||..:.:|:..:  .|......|.:.|:.||:     .:..::|.....:| |.|:.|
Mosquito   153 TVADFSLLTSITTI--DVTAGHDLSKYANIQRWY-----SQLKESVAGHQDICVEGAIQF 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	20/51 (39%)
		GstA	5..187	CDD:223698	43/162 (27%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	24/119 (20%)
		EF1G	271..376	CDD:279041
GSTD11	XP_313665.4	GstA	1..189	CDD:223698	44/172 (26%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	20/49 (41%)
		GST_C_Delta_Epsilon	88..206	CDD:198287	26/126 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810