DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTT2_ANOGA

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_313052.1	Gene:	GSTT2_ANOGA / 1273989	VectorBaseID:	AGAP004165	Length:	209	Species:	Anopheles gambiae

Alignment Length:	187	Identity:	48/187 - (25%)
Similarity:	82/187 - (43%)	Gaps:	28/187 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AAQYSGAQVKVADNFKF----GETNKSAEFLKKFPGGKVPAFETAEGQ-YLSESNAIAYLLANEQ 80
            |.|.....|.|..|.|:    ...::|.:|.|..|...:|..  .:|. .||||.|....|.::.
Mosquito    15 AVQMVAEAVHVKLNLKYLDLMAGAHRSPQFTKLNPQRTIPTL--VDGSLILSESRAALIYLCDQY 77

  Fly    81 LRGG-------KCPFVQAQVQQWISFADNEIVPASCAWVFPLL--GILPQQKNSTAKQEAEAVLQ 136
              |.       :....:|.|.|.:.|....:.|....:..|.:  ...|..:...|.::|   ::
Mosquito    78 --GDEDNDWYPRDTIQRAIVNQRLFFDACVLYPRFADFYHPQVFGNAAPDGRKRLAFEKA---VE 137

  Fly   137 QLNQKLQDATFLAGERITLADIVVFSSLLH--LYEYVLEPSVRSAFGNVNRWFVTIL 191
            .||..|.:..|:||.::|:|||.:|::|..  ...::|.|.|     :|:||:||::
Mosquito   138 LLNIFLSEHEFVAGSKMTIADISLFATLATACTLGFILRPYV-----HVDRWYVTMV 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	18/62 (29%)
		GstA	5..187	CDD:223698	45/181 (25%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	29/106 (27%)
		EF1G	271..376	CDD:279041
GSTT2_ANOGA	XP_313052.1	GST_N_Delta_Epsilon	2..75	CDD:239343	18/61 (30%)
		GstA	4..190	CDD:223698	48/187 (26%)
		GST_C_Delta_Epsilon	91..205	CDD:198287	29/107 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810