DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTZ1

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_003436289.1	Gene:	GSTZ1 / 1273066	VectorBaseID:	AGAP002898	Length:	263	Species:	Anopheles gambiae

Alignment Length:	214	Identity:	49/214 - (22%)
Similarity:	81/214 - (37%)	Gaps:	49/214 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKGTLYTYPENFRAYKALIAAQYSGA--QVKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEG 63
            |.|..||:|..:..:::..||......  .:|.....|.|......|:.:..|..:|||.: .:|
Mosquito    50 MSKPILYSYWRSSCSWRVRIALNLKEIPYDIKPISLIKSGGEQHCNEYREVNPMEQVPALQ-IDG 113

  Fly    64 QYLSESNAIAY----------LLANEQLRGGK----CPFVQAQVQQWISFADNEIVPASCAWVFP 114
            ..|.||.:|.|          |:..:.|:..|    |..:.:.||.    ..|.||
Mosquito   114 HTLIESVSIMYYLEETRPQRPLMPQDVLKRAKVREICEVIASGVQP----LQNLIV--------- 165

  Fly   115 LLGILPQQKNSTAKQEAEAVLQQLNQKLQDAT--FLAGERITLADIV----VFSSL-----LHLY 168
            |:.:..::|...|:.......:.:.:.|..:.  |..|:.|||||..    ||::.     |..|
Mosquito   166 LIHVGEEKKKEWAQHWITRGFRAIEKLLSTSAGKFCVGDEITLADCCLVPQVFNARRFHVDLRPY 230

  Fly   169 EYVL--------EPSVRSA 179
            ..:|        .|:.|:|
Mosquito   231 PIILRIDRELEGHPAFRAA 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	20/86 (23%)
		GstA	5..187	CDD:223698	47/210 (22%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	24/109 (22%)
		EF1G	271..376	CDD:279041
GSTZ1	XP_003436289.1	GST_N_Zeta	53..127	CDD:239340	19/74 (26%)
		maiA	54..258	CDD:273527	47/210 (22%)
		GST_C_Zeta	142..254	CDD:198300	26/121 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910