DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTU3

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_310012.1	Gene:	GSTU3 / 1271252	VectorBaseID:	AGAP009342	Length:	218	Species:	Anopheles gambiae

Alignment Length:	240	Identity:	61/240 - (25%)
Similarity:	100/240 - (41%)	Gaps:	41/240 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYTYPENFRAYKALIAAQY--SGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEGQYLSE 68
            ||.:|.:..:..||:|.:.  ..|:||:.:.|. || :.:.||:...|...||.. ..|...|.|
Mosquito     6 LYHFPGSPPSRSALLALRNLDLDAEVKIVNLFA-GE-HLADEFVAINPDHTVPTL-VDEDYILWE 67

  Fly    69 SNAIAYLLANEQLRGGKCPFVQAQ------VQQWISFADNEIVPASCAWVFPLLGI----LPQQK 123
            |.|||..|| ||.:.| |....:|      :...:.|....:..|....:..:|..    :||:|
Mosquito    68 SKAIATYLA-EQYKPG-CTLYPSQPKKRGLINHRLYFDSGTLFVALRNVLMTVLRSGETRIPQEK 130

  Fly   124 NSTAKQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFV 188
                |......|::|:..|....::|||..||||:...:::..|.|..:.   ...:.||:.|
Mosquito   131 ----KDAVYKALEKLDSYLDGCDWIAGEECTLADLCALANVATLKEIGVG---MEGYANVSGW-- 186

  Fly   189 TILNQKQVQAVVKDYKLCEKALVFDP-KKYAEFQAKTGAAKPQQQ 232
                          |:.|.:...||. ::.|.|......:|.::|
Mosquito   187 --------------YERCRELPGFDENEEGASFLGNAFKSKLEEQ 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	26/74 (35%)
		GstA	5..187	CDD:223698	52/192 (27%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	25/128 (20%)
		EF1G	271..376	CDD:279041
GSTU3	XP_310012.1	GstA	4..203	CDD:223698	57/224 (25%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	26/74 (35%)
		GST_C_Delta_Epsilon	91..207	CDD:198287	28/138 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810