DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GSTU1

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_309135.1	Gene:	GSTU1 / 1270441	VectorBaseID:	AGAP000947	Length:	233	Species:	Anopheles gambiae

Alignment Length:	208	Identity:	51/208 - (24%)
Similarity:	83/208 - (39%)	Gaps:	45/208 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SAEFLKKFPGGKVPAFETAEGQYLSESNAIAYLLANEQLRGGKC----PFVQAQVQQWISFADNE 103
            :||:.|..|..::|..:. :|.:|||||||...|..:.......    |..:|.|...:.|....
Mosquito    40 TAEYEKMNPQKEIPVLDD-DGFFLSESNAILQYLCEKYAPTSDLYPNDPKDRALVNHRLCFNLAF 103

  Fly   104 IVPASCAWVF-PL--------LGILPQQKNSTAKQEAEAVLQQLNQKLQDATFLAGERITLADIV 159
            :.|...|:|. |:        :|:   :|...|....|..||:...:     :.||..:|:||..
Mosquito   104 LYPQISAYVMAPIFFDYERTAIGL---KKLHLALAAFETYLQRTGTR-----YAAGSGLTIADFP 160

  Fly   160 VFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKAL----VFDPKKYAEF 220
            :.||::.| |.:       .||...|:       .:|||....:|....:|    ....::.|||
Mosquito   161 LVSSVMCL-EAI-------GFGLGERY-------PKVQAWYDGFKQAHPSLWAIAAKGMEEIAEF 210

  Fly   221 QAK----TGAAKP 229
            :..    ||...|
Mosquito   211 EKNPPDLTGMVHP 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	14/35 (40%)
		GstA	5..187	CDD:223698	40/156 (26%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	29/127 (23%)
		EF1G	271..376	CDD:279041
GSTU1	XP_309135.1	GstA	1..208	CDD:223698	45/191 (24%)
		Thioredoxin_like	1..72	CDD:294274	13/32 (41%)
		GST_C_Delta_Epsilon	88..208	CDD:198287	30/142 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810