DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GPRGR27

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_309027.2	Gene:	GPRGR27 / 1270342	VectorBaseID:	AGAP006716	Length:	407	Species:	Anopheles gambiae

Alignment Length:	163	Identity:	37/163 - (22%)
Similarity:	65/163 - (39%)	Gaps:	34/163 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 AFETAEGQYLSES---NAIAY--LLANEQLRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLL 116
            ||......||:|:   |.|..  :|..:|.|    ||..:.:::......| :.....:..||.:
Mosquito    86 AFFAIRTLYLTENVIVNVIVLFAMLECQQSR----PFYASILKELFELGKN-LHDCDASINFPHV 145

  Fly   117 GILPQQKNSTAKQEAEAVLQQLNQKLQD--------ATFLAGERITLADIVVFSSLLHLYEY-VL 172
            ..:      |.:....|||......|.|        .|||....:.:...|:  ::|.||:| .|
Mosquito   146 EAI------TDRLLVCAVLYFSTSSLVDWWADYDPSCTFLCHSVLYILPNVI--NVLALYQYAAL 202

  Fly   173 EPSVRSAFGNVNRWFVTIL---NQKQVQAVVKD 202
            :..|.:.:.:||    ::|   :..|.:..|:|
Mosquito   203 QLIVAACYRSVN----SVLARYHDHQARPKVRD 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	8/26 (31%)
		GstA	5..187	CDD:223698	33/143 (23%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	25/125 (20%)
		EF1G	271..376	CDD:279041
GPRGR27	XP_309027.2	7tm_7	20..402	CDD:285581	37/163 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900