DRSC/TRiP Functional Genomics Resources

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Protein Alignment nerfin-1 and insm1a

DIOPT Version :9

Sequence 1:NP_524783.1 Gene:nerfin-1 / 44786 FlyBaseID:FBgn0028999 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_991207.1 Gene:insm1a / 402941 ZFINID:ZDB-GENE-040426-1810 Length:383 Species:Danio rerio


Alignment Length:312 Identity:104/312 - (33%)
Similarity:149/312 - (47%) Gaps:81/312 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 SSSEVQGEVTKVEELP-VKPPTPPQSPAGKRKLSRESYDDEPAKMAKKEEE-----------VPV 151
            |..:.||... .:::| .:.|..|........:.|..|  .|.:...:|.|           .|:
Zfish    22 SEEDEQGAFV-AQDVPCARRPVSPVQFGNPETVYRAMY--SPTRPVSREHERACLERRFNLGSPI 83

  Fly   152 ETVESTPAKPVKVAESAPKTNKASTSS--------------------GKPS--RNKATRKLKF-D 193
             :.||.||.| ..::.||...|..||:                    |||:  :.||.|||:| |
Zfish    84 -SAESFPAAP-NCSDQAPVDLKIGTSNSNRTGTTVTTKRPASDTERKGKPASKKAKAMRKLQFED 146

  Fly   194 EETSSPVSGTVIR--PLEDITDGSMQYSNGDIDPKYNIVEITEETKAELAAIKNVIGDYVCRLCK 256
            |.|:|||.|..|:  |:|                        ::.:::.|:....:|::||:||:
Zfish   147 EMTTSPVLGLKIKEGPVE------------------------QKPRSQCASGDKPLGEFVCQLCR 187

  Fly   257 IKFEDAFGLARHRCACIVLLEYRCPECGKQFNCPANLASHRRWHKPRKEASKKENRNTTNQPEKQ 321
            ..:.|.|.||:|:|:.||.:|||||||.|.|:||||||||||||||::.|..    |.|..|||:
Zfish   188 EAYADPFSLAQHKCSRIVRIEYRCPECDKLFSCPANLASHRRWHKPKQSAES----NKTPAPEKE 248

  Fly   322 QQ----------VEKKSEEELAFDCQECGKKFKRAAYLRKHQLT-HQKKEKP 362
            :.          :.:...|:..:|||.|||||||.|||:||... |...|||
Zfish   249 ETSSDRDTPSPGLSESGSEDGLYDCQHCGKKFKRQAYLKKHVTAHHDAPEKP 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nerfin-1NP_524783.1 C2H2 Zn finger 252..272 CDD:275368 9/19 (47%)
C2H2 Zn finger 280..300 CDD:275368 16/19 (84%)
zf-C2H2 334..356 CDD:278523 15/22 (68%)
C2H2 Zn finger 336..356 CDD:275368 14/20 (70%)
insm1aNP_991207.1 SNAG domain. /evidence=ECO:0000250|UniProtKB:Q63ZV0 1..20
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 99..141 9/41 (22%)
C2H2 Zn finger 183..203 CDD:275368 9/19 (47%)
C2H2 Zn finger 211..231 CDD:275368 16/19 (84%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 229..269 12/43 (28%)
zf-C2H2 271..293 CDD:278523 15/21 (71%)
C2H2 Zn finger 273..293 CDD:275368 14/19 (74%)
C2H2 Zn finger 316..335 CDD:275368
C2H2 Zn finger 344..365 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170579510
Domainoid 1 1.000 54 1.000 Domainoid score I11215
eggNOG 1 0.900 - - E1_KOG3993
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4454
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0002683
OrthoInspector 1 1.000 - - mtm6617
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR15065
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3291
SonicParanoid 1 1.000 - - X1791
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
1211.880

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