DRSC/TRiP Functional Genomics Resources

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Protein Alignment nerfin-1 and ZNF707

DIOPT Version :9

Sequence 1:NP_524783.1 Gene:nerfin-1 / 44786 FlyBaseID:FBgn0028999 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001094068.1 Gene:ZNF707 / 286075 HGNCID:27815 Length:371 Species:Homo sapiens


Alignment Length:351 Identity:67/351 - (19%)
Similarity:107/351 - (30%) Gaps:120/351 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 ASLPPKYRSRYLNLKTRCEIPLDLTLKLPSPLPSSDVPMAATFAEVYSENTSASSSEVQGEVTKV 110
            |.|.|..|:.|.::                        |...|:.|.:....:...::...:.:.
Human    23 ACLEPSQRALYRDV------------------------MLDNFSSVAALGFCSPRPDLVSRLEQW 63

  Fly   111 EELPVKPPTPPQSPA---GKRKLSRESYD-----DEPAKMAKK---------------------- 145
            ||..|:....|:..|   |.|..:|:|.|     |.||...||                      
Human    64 EEPWVEDRERPEFQAVQRGPRPGARKSADPKRPCDHPAWAHKKTHVRRERAREGSSFRKGFRLDT 128

  Fly   146 -EEEVPVETVESTPAKPVKVAESAP---KTNKASTSSGKPSRNKATRKLKFDEETSSPVSGTVIR 206
             :.::|....|.|.|||.    :.|   .|.:.....|:..|.|                     
Human   129 DDGQLPRAAPERTDAKPT----AFPCQVLTQRCGRRPGRRERRK--------------------- 168

  Fly   207 PLEDITDGSMQYSNGDIDPKYNIVEITEETKAELAAIKNVIGDYVCRLCKIKFEDAFGLARHRCA 271
                                        :...||:        ::|..|.........|..|:..
Human   169 ----------------------------QRAVELS--------FICGTCGKALSCHSRLLAHQTV 197

  Fly   272 CIVLLEYRCPECGKQFNCPANLASHRRWHKPRKEASKKENRNTTNQPEKQQQVEKKSEEELAFDC 336
            ......:.|||||:.|...:||..|::.|...|....:......:..::..|..|...|...:.|
Human   198 HTGTKAFECPECGQTFRWASNLQRHQKNHTREKPFCCEACGQAFSLKDRLAQHRKVHTEHRPYSC 262

  Fly   337 QECGKKFKRAAYLRKHQLTHQKKEKP 362
            .:|||.||:.:.|.:|||.| ..|:|
Human   263 GDCGKAFKQKSNLLRHQLVH-TGERP 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nerfin-1NP_524783.1 C2H2 Zn finger 252..272 CDD:275368 4/19 (21%)
C2H2 Zn finger 280..300 CDD:275368 9/19 (47%)
zf-C2H2 334..356 CDD:278523 10/21 (48%)
C2H2 Zn finger 336..356 CDD:275368 10/19 (53%)
ZNF707NP_001094068.1 KRAB 8..68 CDD:214630 10/68 (15%)
KRAB 8..47 CDD:279668 8/47 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..143 15/71 (21%)
C2H2 Zn finger 178..198 CDD:275368 4/19 (21%)
COG5048 <187..366 CDD:227381 29/102 (28%)
C2H2 Zn finger 206..226 CDD:275368 9/19 (47%)
zf-H2C2_2 218..242 CDD:290200 5/23 (22%)
C2H2 Zn finger 234..254 CDD:275368 2/19 (11%)
zf-C2H2 260..282 CDD:278523 10/21 (48%)
C2H2 Zn finger 262..282 CDD:275368 10/19 (53%)
zf-H2C2_2 274..299 CDD:290200 7/15 (47%)
C2H2 Zn finger 290..310 CDD:275368
zf-H2C2_2 302..325 CDD:290200
C2H2 Zn finger 318..338 CDD:275368
C2H2 Zn finger 346..366 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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