DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ady43A and zgc:136858

DIOPT Version :9

Sequence 1:	NP_651995.1	Gene:	Ady43A / 44750	FlyBaseID:	FBgn0026602	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001035392.1	Gene:	zgc:136858 / 678543	ZFINID:	ZDB-GENE-060421-6632	Length:	700	Species:	Danio rerio

Alignment Length:	393	Identity:	83/393 - (21%)
Similarity:	135/393 - (34%)	Gaps:	114/393 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GNPPTDDTQGAFHTPRKVICFGNVLLDRLVQLEDPQLLERFGLELGSKGELDMEKLNQLAAEASE 78
            ||..|..|... ....|.|..|.:.:|.:.:....:||  ||
Zfish   336 GNIKTQKTMDQ-KMDSKTIVIGGINVDFIAKGTTKKLL--FG----------------------- 374

  Fly    79 SSRCLTNP-------GGSALNTARILKQLGTDALFFGAVGADKHAEELRQIIR--DRGIEARLQT 134
                .|||       ||...|.|..|.:||...||..|:|.|.|::.:....:  |....||||
Zfish   375 ----QTNPGSVCQSFGGVGRNIADCLSRLGHKPLFISAIGKDSHSDAVLNYCKHMDTSAVARLQ- 434

  Fly   135 VEDAHTGQCVCLMYQDNPTLYANIG---ASAQFEVQTLSHAVSH---------EGQ------SFL 181
              |..|. ..|.:..::..|...:|   ...|.:.|.:|..|..         :|.      :::
Zfish   435 --DQRTA-TYCAVITESGELSLGLGDMDIHQQIQEQYVSQFVDQLSSASLIVLDGNIPVSTINYV 496

  Fly   182 RPVERKQILYVEGFFVPQRSD-VCDYIVQHLVRERRRLALNLSAPYIVR---KNHQAMM----KL 238
            ..:.:|..:.|  :|.|..:| .|...:....:     ||..::|.:..   .||...:    :|
Zfish   497 CRIAKKHAVPV--WFEPTDADKACKPFLSESWK-----ALAFTSPNLTELCTMNHTLGLPTPAEL 554

  Fly   239 ARAAFFLFGNRQEFEALAEAAGGFRNVDELADHLLQSGGTKVIFVTNGSAGVQVITNYVEELAPP 303
            .|:...:.|..   .||:.         .|.:||      ..:.||.||.||.|...:     ..
Zfish   555 PRSLEDVLGCA---PALSR---------PLLEHL------HCVVVTLGSLGVLVCGEH-----EA 596

  Fly   304 GPVSFEDFRAQR---------------VEQLVDATGAGDAFVAGFLHAWLEKRSLGECIRMASSV 353
            |.|:.:..:.:|               .|:.|:.:||||:|....:...|:......|::|....
Zfish   597 GTVNLQPRKQKRKARLCAVHYPALTLSSEETVNVSGAGDSFAGAMMVGILQGLHTDSCVQMGLLA 661

  Fly   354 AAK 356
            |.:
Zfish   662 ARR 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ady43A	NP_651995.1	adenosine_kinase	28..366	CDD:238573	79/379 (21%)
Ady43A	NP_651995.1	PTZ00247	28..366	CDD:240328	79/379 (21%)
zgc:136858	NP_001035392.1	Indigoidine_A	33..322	CDD:282130
zgc:136858	NP_001035392.1	YeiC_kinase_like	351..668	CDD:238916	79/377 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910