Protein Alignment Ady43A and RBKS

DIOPT Version :9

• Sequence 1: NP_651995.1
• Gene: Ady43A / 44750
• FlyBaseID: FBgn0026602
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_071411.1
• Gene: RBKS / 64080
• HGNCID: 30325
• Length: 322
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 82/350 - (23%)
• Similarity: 133/350 - (38%)
• Gaps: 79/350 - (22%)

  Fly    31 VICFGNVLLDRLVQLED--PQLLE-----RFGLELGSKGELDMEKLNQLAAEASESSRCLTNPGG 88
            |:..|:.:.| ||.|..  |:..|     :|.:..|.||.....:..:|.|..|
Human    18 VVVVGSCMTD-LVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTS----------- 70

  Fly    89 SALNTARILKQLGTDALFFGAVGADKHAEELRQIIRDRGIEARLQTVEDAHTGQCVCLMYQDNPT 153
                   ::.::|.|:  ||    :.:.|.|:|  .|...|...|| :||.||....::..:...
Human    71 -------MVCKVGKDS--FG----NDYIENLKQ--NDISTEFTYQT-KDAATGTASIIVNNEGQN 119

  Fly   154 LYANI-GASAQFEVQTLSHAVSHEGQSFLRPVERKQILYVEGFFVPQRSDVCDYIVQHLVRERRR 217
            :...: ||:.....:.|..|.:        .:.|.:::..:....|..|      ::.|...||.
Human   120 IIVIVAGANLLLNTEDLRAAAN--------VISRAKVMVCQLEITPATS------LEALTMARRS 170

  Fly   218 LALNL--SAPYIVRKNHQAMMKLARAAFFLFG-----NRQEFEALAE-AAGGFRNVDELADHLLQ 274
            ....|  .||.|...:.|         |:...     |..|.|.|.. ..|...:..|.|..||:
Human   171 GVKTLFNPAPAIADLDPQ---------FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLK 226

  Fly   275 SGGTKVIFVTNGSAGVQVITNYVEELAPPGPVSFEDFRAQRVEQLVDATGAGDAFVA--GFLHAW 337
            . |.:|:.:|.|:.|..|::....|   |..:..|..:|      ||.|||||:||.  .|..|:
Human   227 R-GCQVVIITLGAEGCVVLSQTEPE---PKHIPTEKVKA------VDTTGAGDSFVGALAFYLAY 281

  Fly   338 LEKRSLGECIRMASSVAAKVVTQVG 362
            ....||.:.:..::.:||..|...|
Human   282 YPNLSLEDMLNRSNFIAAVSVQAAG 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ady43A	NP_651995.1	adenosine_kinase	28..366	CDD:238573	81/349 (23%)
		PTZ00247	28..366	CDD:240328	81/349 (23%)
RBKS	NP_071411.1	D_ribokin_bact	22..318	CDD:274000	80/345 (23%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:P0A9J6, ECO:0000255|HAMAP-Rule:MF_03215	25..27		0/1 (0%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:P0A9J6, ECO:0000255|HAMAP-Rule:MF_03215	53..57		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810