| Sequence 1: | NP_611177.1 | Gene: | NiPp1 / 44748 | FlyBaseID: | FBgn0026402 | Length: | 383 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_054829.2 | Gene: | PPP1R8 / 5511 | HGNCID: | 9296 | Length: | 351 | Species: | Homo sapiens |
| Alignment Length: | 389 | Identity: | 179/389 - (46%) |
|---|---|---|---|
| Similarity: | 230/389 - (59%) | Gaps: | 60/389 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 ANS------YDIPSWAGKPPTGLHLDVLKDDKLVQKLMVDEKRCYLFGRNSQMNDFCIDHASCSR 60
Fly 61 VHSAFVYHKHLNIAYLVDLGSTHGTFIGTLRLEAHKPTQLQINSTFHFGASTRNYILRERPSGHH 125
Fly 126 SNIMEDLPLSETSD--GALLGLPESQTELDNLTEYNTAHNRRISMLGIDDDTNMRKQNALKQGRR 188
Fly 189 TRNVTFNDEEIVINPEDVDPNVGRFRNLVQTTVVPAKRARCDVNHMGIHSGNSSLSSANAAHVHQ 253
Fly 254 MFQQSLVDMKQQHREMPPPNAVLHSPTNSLYQGLPAEMHGKGDLEP--ISPLSIGSKLGLLLPNP 316
Fly 317 APEV--LPVYDEAVETSTLAQKLAVANANVRRFGEDPHDSSGEGDSLCPQKKKYAKEAWPGRKP 378 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| NiPp1 | NP_611177.1 | FHA | 18..110 | CDD:238017 | 59/91 (65%) |
| FHA | <40..>87 | CDD:224630 | 32/46 (70%) | ||
| PPP1R8 | NP_054829.2 | Interaction with CDC5L, SF3B1 and MELK. /evidence=ECO:0000269|PubMed:10827081, ECO:0000269|PubMed:12105215, ECO:0000269|PubMed:14699119 | 1..142 | 83/136 (61%) | |
| FHA | 27..119 | CDD:238017 | 59/91 (65%) | ||
| WASH_WAHD | <98..>212 | CDD:403229 | 56/115 (49%) | ||
| Interaction with EED. /evidence=ECO:0000269|PubMed:12788942 | 143..224 | 44/82 (54%) | |||
| Nuclear localization signal 1. /evidence=ECO:0000269|PubMed:11034904 | 185..209 | 7/25 (28%) | |||
| Involved in PP-1 inhibition | 191..200 | 2/9 (22%) | |||
| Involved in PP-1 binding | 200..203 | 1/2 (50%) | |||
| Nuclear localization signal 2. /evidence=ECO:0000269|PubMed:11034904 | 210..240 | 22/35 (63%) | |||
| Interaction with EED. /evidence=ECO:0000269|PubMed:12788942 | 310..329 | 6/29 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 316..351 | 19/45 (42%) | |||
| RNA-binding | 330..351 | 14/16 (88%) | |||
| Involved in PP-1 inhibition | 331..337 | 4/5 (80%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165154610 | |
| Domainoid | 1 | 1.000 | 137 | 1.000 | Domainoid score | I4908 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1880 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H8555 | |
| Inparanoid | 1 | 1.050 | 290 | 1.000 | Inparanoid score | I2816 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4121 |
| OMA | 1 | 1.010 | - | - | QHG49326 | |
| OrthoDB | 1 | 1.010 | - | - | D400304at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0005513 | |
| OrthoInspector | 1 | 1.000 | - | - | oto89882 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_106306 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR23308 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3572 |
| SonicParanoid | 1 | 1.000 | - | - | X3930 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 17 | 16.750 | |||||