Protein Alignment msk and MTR4

DIOPT Version :10

• Sequence 1: NP_524780.1
• Gene: msk / 44747
• FlyBaseID: FBgn0026252
• Length: 1049
• Species: Drosophila melanogaster
• Sequence 2: NP_012485.1
• Gene: MTR4 / 853397
• SGDID: S000003586
• Length: 1073
• Species: Saccharomyces cerevisiae
• Alignment Length: 938
• Identity: 175/938 - (18%)
• Similarity: 301/938 - (32%)
• Gaps: 343/938 - (36%)

  Fly   276 YGSPSNVVS-EKYQ----KFAEWYLPTF------SQGVLEVLLKILDQYRNRVYVSPRVLTDV-- 327
            |.||...:| :||:    :|.:..|.|.      ..|.|.:..:||   |:.:|....|:.:|
Yeast   197 YTSPIKALSNQKYRELLAEFGDVGLMTGDITINPDAGCLVMTTEIL---RSMLYRGSEVMREVAW 258

  Fly   328 -----LNYLKNAVSHAYTWK---LIKPHMVA-VIQDVIFP-IMSFTDSDQELW----ESDPYEYI 378
                 ::|:::. .....|:   ::.|..|. |......| .|.|.:     |    .|.|...:
Yeast   259 VIFDEVHYMRDK-ERGVVWEETIILLPDKVRYVFLSATIPNAMEFAE-----WICKIHSQPCHIV 317

  Fly   379 RLKFDIFEDYATPV-----PAAQSLLHSMCKK----RKGILPKAMATIM-QIITSPNA-DNKQKD 432
            ...|     ..||:     ||....::.:..:    |:....||||:|. ||...||: |::.|.
Yeast   318 YTNF-----RPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKK 377

  Fly   433 GALHMIGTLADVLLKKASYRDQVESMLTTYVFPEFQNPAGHMRARACWVLHYFCDVQIKNPQVLA 497
            |..:..|:      .|...:..:..::                 :..|...|       ||.::.
Yeast   378 GQTYKGGS------AKGDAKGDIYKIV-----------------KMIWKKKY-------NPVIVF 412

  Fly   498 EIMRLTTNALLTDKELPVKVEAAIGLQMFISSQDEAPQYVEAQIKEITKELLTIIRETENE---- 558
            ...:...      :||.:|:.     ::..:|.||     :..:.:|....:.::.||:.|
Yeast   413 SFSKRDC------EELALKMS-----KLDFNSDDE-----KEALTKIFNNAIALLPETDRELPQI 461

  Fly   559 -DLTNVMQKIVCTFTEQLLPVATEICQHL----------AT-TFSQVLE---------------- 595
             .:..::::.:......|||:..|:.:.|          || |||..|.
Yeast   462 KHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVFTSVRKWDG 526

  Fly   596 ------------------SEEGSDEKAITAMSLLNTIETLLSVMEEHPDVLLNLHPIVINVVGHI 642
                              ...|.|::.|..|.:...:|         |.|...:      |.|.
Yeast   527 QQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEKME---------PQVAKGM------VKGQ- 575

  Fly   643 FQHNITDFYEETFSLVYD-----LTAKAISPEMWQMLELIYQVFKK------------------D 684
                 .|..:..|.|.|:     :..:.||||.  |||..:..|:.                  |
Yeast   576 -----ADRLDSAFHLGYNMILNLMRVEGISPEF--MLEHSFFQFQNVISVPVMEKKLAELKKDFD 633

  Fly   685 GIDY--------FIDIMPALHNY-----VTVDTPA----FLSNPNRLL-------------AILD 719
            ||:.        :.:|..|:..|     ..|..||    || .|.||:             |::|
Yeast   634 GIEVEDEENVKEYHEIEQAIKGYREDVRQVVTHPANALSFL-QPGRLVEISVNGKDNYGWGAVVD 697

  Fly   720 MCKTMLTSSPGEDPECHAAKLMEVIILQCKGQIDSVIHMFVEL--ALSRLTREVQSSELRTMCLQ 782
            ..|.:...:|......|.:.::.|::...  .|||.:::....  .|....|..:..| :::|..
Yeast   698 FAKRINKRNPSAVYTDHESYIVNVVVNTM--YIDSPVNLLKPFNPTLPEGIRPAEEGE-KSICAV 759

  Fly   783 VVIA----------ALYYNPQLLLSILDKMSQQNNDSISAHF---------IKQWLHDTDCFLGI 828
            :.|.          .||....:..|...:...::...::..|         :|....:.:.||.:
Yeast   760 IPITLDSIKSIGNLRLYMPKDIRASGQKETVGKSLREVNRRFPDGIPVLDPVKNMKIEDEDFLKL 824

  Fly   829 HDRKLCVLGLCTLISLGEAKPQV-LSEVAGKIVPALILLFDGLKRAYESRAQEEEEDEEEEDGDD 892
            . :|:.||.  |.:|.......: |.|:.||.                ||..:..||.::
Yeast   825 M-KKIDVLN--TKLSSNPLTNSMRLEELYGKY----------------SRKHDLHEDMKQ----- 865

  Fly   893 CEEALSSDEDDMDEMAPDYLDKLAEFAKTKGNESGFEVKAEIKDDDADSDGDAEESVGDLNETGL 957
                                      .|.|.:||    :|.|:.||..........:|
Yeast   866 --------------------------LKRKISES----QAVIQLDDLRRRKRVLRRLG------- 893

  Fly   958 ESFTTPIDDEENESAIDEYWTFKEVITALSAQDQAWYALLT--------SNLTPEQAKALQEVVV 1014
              |.||.|..|.:.         .|...:|:.|:   .|||        :.|.||||.||.....
Yeast   894 --FCTPNDIIELKG---------RVACEISSGDE---LLLTELIFNGNFNELKPEQAAALLSCFA 944

  Fly  1015 TADQRKAAKESKLIEKQGGFAFPQTAVP 1042
            ..::.|.|...|          |:.|.|
Yeast   945 FQERCKEAPRLK----------PELAEP 962

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msk	NP_524780.1	SXM1	4..1013	CDD:227943	169/907 (19%)
MTR4	NP_012485.1	Dob10	143..1068	CDD:443638	175/938 (19%)