DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msk and mtrex

DIOPT Version :9

Sequence 1:	NP_524780.1	Gene:	msk / 44747	FlyBaseID:	FBgn0026252	Length:	1049	Species:	Drosophila melanogaster
Sequence 2:	NP_999933.1	Gene:	mtrex / 406795	ZFINID:	ZDB-GENE-040426-2854	Length:	1034	Species:	Danio rerio

Alignment Length:	542	Identity:	108/542 - (19%)
Similarity:	188/542 - (34%)	Gaps:	184/542 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 PLNEAMNLLLPMIYQLMVRLLAEQSEQSVLLQKQILKIYYALTQYTLPLDLITKEIFSQWMEICR 235
            |||.|.:|...|:..|   |..|:.....:|:|.    :|....|
Zfish   551 PLNSAFHLTYNMVLNL---LRVEEINPEYMLEKS----FYQFQHY-------------------- 588

  Fly   236 QVADRAVPD----SSHLDDD--------ERTEFPYWKTKKWALHIMVRMFE-----RYG----SP 279
                ||||.    ...|:::        |.:...|:|.::....:...:.|     ||.    .|
Zfish   589 ----RAVPGVVDRMKKLEEEYNAIRIPKEESVVTYYKIRQQLAKLGKEIEEFIHKPRYCLPFLQP 649

  Fly   280 SNVVSEK-------------YQKFAEWYL-----PTFSQGVLEVLLKI-LDQYRNRVYVSPR--- 322
            ..:|..|             :||.:....     |.|   |:|||:.. .|..:|....|.|
Zfish   650 GRLVKVKKEDLDFGWGVVVNFQKKSNVKAGGDLDPLF---VVEVLVHCSKDSVKNAATESARPAG 711

  Fly   323 -------VLTDVLNYLKNAVS--HAYTWKLIKPH-----MVAVIQDV--IFPI-MSFTDSDQELW 370
                   .:..|:.:|..::|  ..|..|.::|:     |:..||:|  .||. :...|...::.
Zfish   712 PAEKGEMQVVPVILHLITSISSVRLYIPKDLRPYDNRQSMLKSIQEVQKRFPDGIPLLDPIDDMG 776

  Fly   371 ESDP-YEYIRLKFDIFED--YATPVPAAQSL--LHSMCKKR----------KGILPKAMATIMQI 420
            ..|| .:.:..|.:.||.  |..|:.:..:|  ::.:|:|:          |..|.|| .|::|:
Zfish   777 IKDPALKKVIQKVEAFEHRMYTHPLHSDPNLEAVYKLCEKKALIAGDIKAAKRELKKA-RTVLQM 840

  Fly   421 ITSPNADNKQKDGALHMIG--TLADVLLKKASYRDQVESMLTTYVFPEFQNPAGHMRARACWVLH 483
                 .:.|.:...|..:|  |.:||:                           .|:.|..
Zfish   841 -----DELKCRKRVLRRLGFATSSDVI---------------------------EMKGRVA---- 869

  Fly   484 YFCDVQIKNPQVLAEIMRLTTNALLTDKELPVKVEAAIGLQ---MFISSQDEAPQYVE------A 539
              |:....:..:|.|:|   .|.|..|    :..|.|..|.   :|..:.:|.|:..|      .
Zfish   870 --CETSSGDELLLTEMM---FNGLFND----LTAEQATALLSCFVFQENANEMPKLTEQLGGPLR 925

  Fly   540 QIKEITKELLTIIRETE---NEDLTNVMQKIVCTFTEQLLPVATEICQHLA--TTFSQVLESEEG 599
            |::|..|.:..:..|.:   :||          ::..|..|...::....|  ::|||:.:..:.
Zfish   926 QMQECAKRIAKVSAEAKLEVDED----------SYLNQFRPHLMDVVYTWANGSSFSQICKMTDV 980

  Fly   600 SDEKAITAMSLLNTIETLLSVM 621
            .:...|..|   ..:|.||..|
Zfish   981 FEGSIIRCM---RRLEELLRQM 999

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msk	NP_524780.1	SXM1	4..1013	CDD:227943	108/542 (20%)
msk	NP_524780.1	IBN_N	24..103	CDD:281761
mtrex	NP_999933.1	Dob10	15..1034	CDD:226947	108/542 (20%)
		DEAD	130..275	CDD:278688
		HELICc	433..521	CDD:197757
		rRNA_proc-arch	577..832	CDD:289976	54/285 (19%)
		DSHCT	860..1027	CDD:285374	36/193 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4581
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900