DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MED6 and med6

DIOPT Version :9

Sequence 1:	NP_001163577.1	Gene:	MED6 / 44728	FlyBaseID:	FBgn0024330	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001016292.1	Gene:	med6 / 549046	XenbaseID:	XB-GENE-967312	Length:	246	Species:	Xenopus tropicalis

Alignment Length:	259	Identity:	116/259 - (44%)
Similarity:	160/259 - (61%)	Gaps:	25/259 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASRQMTNDHLRLSWHDTQMMATLSPQTVMDYFCRKSNPFYDHMCNNETVRMQRLGPEHLHNMIG 65
            ||:..:.::.|.:||.|:..:..|:..||:|||..:||||||..||||.|:||||..:||:.|:|
Frog     1 MAAVDIRDNLLGISWVDSSWIPILNNGTVLDYFSERSNPFYDRTCNNEVVKMQRLTLDHLNQMVG 65

  Fly    66 LEYILLHVAEPILYVIRKQHRHNPSEATPIADYYIIGGTVYKAPDLANVINSRILNTVVNLQSAF 130
            :||||||..||||::||||.|.:|::..|:||||||.|.:|:||||.:|||||:|..|..:||||
Frog    66 IEYILLHAQEPILFIIRKQQRQSPTQVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAF 130

  Fly   131 EEASSYARYHPNKGYTWDFSSNKVFSDRSKSDKKDANSAKDENSGTLFQKQRVDMLLAELLRKFP 195
            :||.||.||||:|||.|.      |.|:.:.||....:.|.|.:.:.||:||||.||.||.:|||
Frog   131 DEAMSYCRYHPSKGYWWH------FKDQEERDKTKPKAKKKEEASSHFQRQRVDALLMELRQKFP 189

  Fly   196 P----------PIPPMLQNLQQPPPAGDDLNTARNASEMNNATGPLDIKTEGVDMKPPPEKKSK 249
            |          |:|......:..|||    .|.:...:     .|:.:..:|...|.||||:.:
Frog   190 PKFIQQKTGEKPVPVEQIKKEAEPPA----ETIKQEEK-----EPVKVAQQGATPKGPPEKRMR 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MED6	NP_001163577.1	Med6	13..139	CDD:282750	72/125 (58%)
med6	NP_001016292.1	Med6	13..139	CDD:368200	72/125 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	160	1.000	Domainoid score	I4019
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3990
Inparanoid	1	1.050	216	1.000	Inparanoid score	I3517
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1251252at2759
OrthoFinder	1	1.000	-	-		FOG0005042
OrthoInspector	1	1.000	-	-		oto104472
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2638
SonicParanoid	1	1.000	-	-		X5378
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090