DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MED6 and mdt-6

DIOPT Version :9

Sequence 1:	NP_001163577.1	Gene:	MED6 / 44728	FlyBaseID:	FBgn0024330	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_504791.3	Gene:	mdt-6 / 179091	WormBaseID:	WBGene00003164	Length:	250	Species:	Caenorhabditis elegans

Alignment Length:	199	Identity:	74/199 - (37%)
Similarity:	123/199 - (61%)	Gaps:	9/199 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASRQMTNDHLRLSWHDTQMMAT-LSPQTVMDYFCRKSNPFYDHMCNNETVRMQ----RLGPEHLH 61
            |:||  ::.|.:|:.:.|.... ::...|:||||.::|.||:....|:.:|||    |...|.|.
Worm    10 AARQ--DNPLHVSFRNPQWPPNFINKDNVLDYFCNQANAFYEMNSCNQQIRMQNIVNRTVEECLR 72

  Fly    62 NMIGLEYILLHVAEPILYVIRKQHRHNPSEATPIADYYIIGGTVYKAPDLANVINSRILNTVVNL 126
            .|.|::|:|.: ::|.|::|.||.|:|.:..:|||.||:|.|:|::|||:.:::.||:|..:..|
Worm    73 TMPGIQYVLWY-SQPPLFIICKQRRNNVTNVSPIAYYYVINGSVHQAPDMYSLVQSRLLGALEPL 136

  Fly   127 QSAFEEASSYARYHPNKGYTWDFSSNKVFSDRSKSDKKDANSAKDENSGTLFQKQRVDMLLAELL 191
            ::||.|.::|:||:..|||.|:| .||....:.:.:||:....|.|:..|.|||.|..|||.:|.
Worm   137 RNAFGEVTNYSRYNTAKGYYWEF-KNKPNVKKREEEKKEDEEEKLEDRSTNFQKTRTMMLLNQLF 200

  Fly   192 RKFP 195
            .:.|
Worm   201 SEMP 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MED6	NP_001163577.1	Med6	13..139	CDD:282750	47/130 (36%)
mdt-6	NP_504791.3	Med6	19..149	CDD:282750	47/130 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162761
Domainoid	1	1.000	98	1.000	Domainoid score	I4530
eggNOG	1	0.900	-	-		E1_COG5097
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3990
Inparanoid	1	1.050	131	1.000	Inparanoid score	I3202
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55402
OrthoDB	1	1.010	-	-		D1251252at2759
OrthoFinder	1	1.000	-	-		FOG0005042
OrthoInspector	1	1.000	-	-		oto19042
orthoMCL	1	0.900	-	-		OOG6_102673
Panther	1	1.100	-	-	LDO	PTHR13104
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2638
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800