DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment san and NAA11

DIOPT Version :9

Sequence 1:	NP_524779.1	Gene:	san / 44724	FlyBaseID:	FBgn0024188	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_116082.1	Gene:	NAA11 / 84779	HGNCID:	28125	Length:	229	Species:	Homo sapiens

Alignment Length:	157	Identity:	34/157 - (21%)
Similarity:	76/157 - (48%)	Gaps:	6/157 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IELGDVTPHNIKQLKKLNTVVFPVSYNDKFYV-DVLEAGELAKLAYYND-IVVGAVCCRI-DNTE 67
            :.:.:..|.::..::..|.:..|.:|..|:|: ..|...:|:.:|...| .:||.|..:: :..:
Human     1 MNIRNAQPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEEPD 65

  Fly    68 NQRRLYIMTLGCLSPYRRLGIGTVMFEHIMNFAEKDGNFDSIFLHVQINNNGAIEFYKK-FGFEI 131
            :....:|.:|.....:||||:...:.:.......::.|...:.|||:.:|..|:..|.. ..|:|
Human    66 DVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRPALHLYSNTLNFQI 130

  Fly   132 VDTKEQYYKRIEPADAHVLQKTLRRTA 158
            .:.:.:||  .:..||:.:::.|.:.|
Human   131 SEVEPKYY--ADGEDAYAMKRDLSQMA 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
san	NP_524779.1	RimI	<27..145	CDD:223532	28/121 (23%)
san	NP_524779.1	Acetyltransf_1	50..130	CDD:278980	17/82 (21%)
NAA11	NP_116082.1	RimI	1..149	CDD:223532	32/149 (21%)
		Interaction with NAA15. /evidence=ECO:0000250	1..58		13/56 (23%)
		Acetyltransf_1	47..122	CDD:278980	16/74 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..229
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810