DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lolal and BTBD18

DIOPT Version :9

Sequence 1:	NP_001163186.1	Gene:	lolal / 44703	FlyBaseID:	FBgn0022238	Length:	127	Species:	Drosophila melanogaster
Sequence 2:	NP_001138573.1	Gene:	BTBD18 / 643376	HGNCID:	37214	Length:	712	Species:	Homo sapiens

Alignment Length:	106	Identity:	37/106 - (34%)
Similarity:	58/106 - (54%)	Gaps:	7/106 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 HLRDEKSFTDVTLACEGQTCKAHKMVLSACSPYFKALLE-ENPSKHPIIILK--DVSYIHLQAIL 86
            |.:....|.||.|..||:...||..:||||||:|...|| |.|::...::|:  .:....|:.::
Human    26 HQQQSDVFCDVLLQAEGEAVPAHCCILSACSPFFTERLERERPAQGGKVVLELGGLKISTLRKLV 90

  Fly    87 EFMYAGEVNVSQEQLPAFLKTADRLKVKGLAETPSSIKREG 127
            :|:|..|:.||||:....|..|.:|:|..|    .|::.||
Human    91 DFLYTSEMEVSQEEAQDVLSAARQLRVSEL----ESLQLEG 127

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lolal	NP_001163186.1	BTB_POZ_BAB-like	32..115	CDD:349624	32/85 (38%)
BTBD18	NP_001138573.1	BTB	24..120	CDD:306997	33/93 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..176
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..355
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..410
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	653..676
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	691..712
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910