DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha36-1 and atp6v1d

DIOPT Version :9

Sequence 1:	NP_651987.1	Gene:	Vha36-1 / 44702	FlyBaseID:	FBgn0022097	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_001017075.1	Gene:	atp6v1d / 549829	XenbaseID:	XB-GENE-973447	Length:	247	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	175/249 - (70%)
Similarity:	210/249 - (84%)	Gaps:	6/249 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGKDRLPIFPSRGAQMLMKARLAGAQKGHGLLKKKADALQMRFRLILGKIIETKTLMGDVMKEA 65
            ||||||:.:||||.||.:|||||.|||.|..|||||:|||.||||.||.||||||.|||:||:||
Frog     1 MSGKDRIEVFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTMRFRQILKKIIETKMLMGEVMREA 65

  Fly    66 AFSLAEAKFTSGDINQVVLQNVTKAQIKIRTKKDNVAGVTLPVFESYQDGSDTYELAGLARGGQQ 130
            ||||||||||:||.:..|:|||.|||:|:|.|:||||||||||||.||:|.|:|||.||||||:|
Frog    66 AFSLAEAKFTAGDFSTTVIQNVNKAQVKVRAKRDNVAGVTLPVFEHYQEGGDSYELTGLARGGEQ 130

  Fly   131 LAKLKKNYQSAVKLLVELASLQTSFVTLDEVIKITNRRVNAIEHVIIPRIDRTLAYIISELDELE 195
            |||||:||..||:|||||||||||||||||.|||||||||||||||||:|:|||:||::||||.|
Frog   131 LAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPKIERTLSYIVTELDERE 195

  Fly   196 REEFYRLKKIQDKKREARIKADAKKA--ELLQQGIDVRQQANIL-DEGDDDVLF 246
            |||||||||||:||:..|.||:.::|  :.:..|   .:.||:| ::.|:|:||
Frog   196 REEFYRLKKIQEKKKIIREKAEKEQAKWKKVSGG---AEPANLLAEDRDEDLLF 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha36-1	NP_651987.1	ATP-synt_D	17..207	CDD:396399	148/189 (78%)
atp6v1d	NP_001017075.1	ATP-synt_D	17..202	CDD:376621	143/184 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	294	1.000	Domainoid score	I1476
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5783
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2370
OMA	1	1.010	-	-		QHG60833
OrthoDB	1	1.010	-	-		D1313938at2759
OrthoFinder	1	1.000	-	-		FOG0003389
OrthoInspector	1	1.000	-	-		otm48055
Panther	1	1.100	-	-	LDO	PTHR11671
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1631
SonicParanoid	1	1.000	-	-		X2286
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110