DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha36-1 and ATP6V1D

DIOPT Version :9

Sequence 1:	NP_651987.1	Gene:	Vha36-1 / 44702	FlyBaseID:	FBgn0022097	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_057078.1	Gene:	ATP6V1D / 51382	HGNCID:	13527	Length:	247	Species:	Homo sapiens

Alignment Length:	247	Identity:	179/247 - (72%)
Similarity:	209/247 - (84%)	Gaps:	2/247 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGKDRLPIFPSRGAQMLMKARLAGAQKGHGLLKKKADALQMRFRLILGKIIETKTLMGDVMKEA 65
            ||||||:.|||||.||.:|||||.|||.|..|||||:|||.:|||.||.||||||.|||:||:||
Human     1 MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETKMLMGEVMREA 65

  Fly    66 AFSLAEAKFTSGDINQVVLQNVTKAQIKIRTKKDNVAGVTLPVFESYQDGSDTYELAGLARGGQQ 130
            ||||||||||:||.:..|:|||.|||:|||.||||||||||||||.|.:|:|:|||.||||||:|
Human    66 AFSLAEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVTLPVFEHYHEGTDSYELTGLARGGEQ 130

  Fly   131 LAKLKKNYQSAVKLLVELASLQTSFVTLDEVIKITNRRVNAIEHVIIPRIDRTLAYIISELDELE 195
            |||||:||..||:|||||||||||||||||.|||||||||||||||||||:|||||||:||||.|
Human   131 LAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRIERTLAYIITELDERE 195

  Fly   196 REEFYRLKKIQDKKREARIKADAKKAELLQQGIDVRQQANIL-DEGDDDVLF 246
            |||||||||||:||:..:.|:: |..|..:...:|.:.||:| :|.|:|:||
Human   196 REEFYRLKKIQEKKKILKEKSE-KDLEQRRAAGEVLEPANLLAEEKDEDLLF 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha36-1	NP_651987.1	ATP-synt_D	17..207	CDD:396399	151/189 (80%)
ATP6V1D	NP_057078.1	ATP-synt_D	17..207	CDD:396399	151/189 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159521
Domainoid	1	1.000	296	1.000	Domainoid score	I1476
eggNOG	1	0.900	-	-		E1_COG1394
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5783
Inparanoid	1	1.050	337	1.000	Inparanoid score	I2392
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60833
OrthoDB	1	1.010	-	-		D1313938at2759
OrthoFinder	1	1.000	-	-		FOG0003389
OrthoInspector	1	1.000	-	-		otm40857
orthoMCL	1	0.900	-	-		OOG6_101069
Panther	1	1.100	-	-	LDO	PTHR11671
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1631
SonicParanoid	1	1.000	-	-		X2286
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800