Protein Alignment ergic53 and LMAN2L

DIOPT Version :10

• Sequence 1: NP_524776.1
• Gene: ergic53 / 44679
• FlyBaseID: FBgn0035909
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001135764.1
• Gene: LMAN2L / 81562
• HGNCID: 19263
• Length: 359
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 86/275 - (31%)
• Similarity: 138/275 - (50%)
• Gaps: 31/275 - (11%)

  Fly    26 PGAVGVHRRFEY---KYSFKPPYLAQKDGTVPFWEYGGNAIASSESVRVAPSLRSQKGAIWTKSQ 87
            |..||..:.|||   ::|...||.....|:...|...|||:..::.:|:.|.::|::||:|.:..
Human    39 PQQVGAGQTFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVP 103

  Fly    88 TNFDWWDVEIVFRVTGRGR--IGADGLAFWYTTEKGDYNGPVFGSSDRWNGLAIMFDSFDNDNKH 150
            .....|::::.|::.|:|:  :..||||.|||.::.. .|||||:.|::.||.:..|::.|:.|.
Human   104 CFLRDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQ-PGPVFGNMDKFVGLGVFVDTYPNEEKQ 167

  Fly   151 NN--------------PYISAVLNDGTKLYDHAEDGTTQLLSGCLRDFRNKPFPTRARIEYYNNV 201
            ..              |||||::|:|:..|||..||....|.||....||..:.|...|.|....
Human   168 QEAQKRRYSPGVQRVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRH 232

  Fly   202 LTVMIHNGMSNNNDDYELCLRADGVNLPKNGYFGISAATGGLADDHDVFHFLTTSLHAAGQVQEQ 266
            ||:|:.   .:...::..|:...||.||:..|||.|:.||.|:|:|||.......|......:|:
Human   233 LTIMMD---IDGKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEE 294

  Fly   267 --------PKVENQE 273
                    |.|:|.:
Human   295 KLHRDVFLPSVDNMK 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ergic53	NP_524776.1	lectin_ERGIC-53_ERGL	33..258	CDD:173890	78/243 (32%)
		HEC1	<267..>421	CDD:444066	3/7 (43%)
LMAN2L	NP_001135764.1	lectin_L-type	50..309	CDD:472686	81/262 (31%)