back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ergic53 and Lman1

DIOPT Version :9

Sequence 1:	NP_524776.1	Gene:	ergic53 / 44679	FlyBaseID:	FBgn0035909	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001165533.1	Gene:	Lman1 / 70361	MGIID:	1917611	Length:	517	Species:	Mus musculus

Alignment Length:	528	Identity:	219/528 - (41%)
Similarity:	323/528 - (61%)	Gaps:	41/528 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RPTFLAILCFLAWNPSSEATGN--LSPGAVGV-----HRRFEYKYSFKPPYLAQKDGTVPFWEYG 59
            |..|.|:|...:....|:.||.  .:|||.|.     |||||||||||.|:|.|.|||||||.:.
Mouse    14 RSFFCALLLSFSQFTGSDGTGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHA 78

  Fly    60 GNAIASSESVRVAPSLRSQKGAIWTKSQTNFDWWDVEIVFRVTGRGRIGADGLAFWYTTEKGDYN 124
            ||||.|::.:|:||||:||:|::|||::..|:.|:||:.|||||||||||||||.|||..:| .:
Mouse    79 GNAIPSADQIRIAPSLKSQRGSVWTKAKAAFENWEVEVTFRVTGRGRIGADGLAIWYTENQG-LD 142

  Fly   125 GPVFGSSDRWNGLAIMFDSFDNDNKHNNPYISAVLNDGTKLYDHAEDGTTQLLSGCLRDFRNKPF 189
            ||||||:|.|||:.|.|||||||.|.|||.|..:.|:|...|||..||.||.|:.|.|||||||:
Mouse   143 GPVFGSADTWNGVGIFFDSFDNDGKKNNPAIVVIGNNGQINYDHQNDGATQALASCQRDFRNKPY 207

  Fly   190 PTRARIEYYNNVLTVMIHNGMSNNNDDYELCLRADGVNLPKNGYFGISAATGGLADDHDVFHFLT 254
            |.||:|.||...|||||:||.:.:.:|||.|.:.:.:.:|..|:||||||||||||||||..|||
Mouse   208 PVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLT 272

  Fly   255 TSLHAAGQVQEQPKVE------NQEKLTQEYKEYQDKLEKQKQEYKKDHPDEHKDEEDWEEFYES 313
            ..|...|  :|.|..|      .:||..:|::.:|.:|:|:|:|::|.|||......|  :.:||
Mouse   273 FQLTEPG--KEPPTAEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAD--DIFES 333

  Fly   314 ENQRELRQIWQGQSQIADHLRELSRKVDEIIGRQETTLSLVSRNAGQALPPPAAGGVPQQQLPVG 378
            ...|||||:::||::|...:::|:|::|.|:..|...:|.::....:     ...|.|.|.   |
Mouse   334 IGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISR-----RGAGTPGQP---G 390

  Fly   379 AVSRSDVDLLLTNQNMLLSSIREIRQLVGDINVRTDNIQTNQKHAPTAQIQSTGYDVQTLIAEMR 443
            .||:.::|.::.:|..:|..:.|::..:.:    |..:.:..:|..:|.:    |:......:::
Mouse   391 QVSQQELDTVVKSQQEILRQVNEVKNSMSE----TVRLVSGIQHPGSAGV----YETTQHFMDIK 447

  Fly   444 DGMNQVKQGITHVGQRLAAPQGAAQVANCPT----GNCVGVTLFLSVTVVQLLLVFIYNVFKNRS 504
            :.::.||:.|..:.|| :.|..  :...||.    .:|:....|:...|||.:|...|.:::.:.
Mouse   448 EHLHVVKRDIDSLAQR-SMPSN--EKPKCPDLPPFPSCLSTIHFVIFVVVQTVLFVGYIMYRTQQ 509

  Fly   505 EAQAKKFY 512
            ||.||||:
Mouse   510 EAAAKKFF 517

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.