back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ergic53 and Lman1

DIOPT Version :9

Sequence 1:	NP_524776.1	Gene:	ergic53 / 44679	FlyBaseID:	FBgn0035909	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_446338.1	Gene:	Lman1 / 116666	RGDID:	71020	Length:	517	Species:	Rattus norvegicus

Alignment Length:	528	Identity:	222/528 - (42%)
Similarity:	322/528 - (60%)	Gaps:	47/528 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FLAILCFLAWNPSSEATGN--LSPGAVGV-----HRRFEYKYSFKPPYLAQKDGTVPFWEYGGNA 62
            |.|:|...:....|:..|.  .:|||.|.     |||||||||||.|:|.|.|||||||.:.|||
  Rat    17 FCALLLSFSQFVGSDGMGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNA 81

  Fly    63 IASSESVRVAPSLRSQKGAIWTKSQTNFDWWDVEIVFRVTGRGRIGADGLAFWYTTEKGDYNGPV 127
            |.|::.:|:||||:||:|::|||::..|:.|:||:.|||||||||||||||.|||..:| .:|||
  Rat    82 IPSADQIRIAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYTENQG-LDGPV 145

  Fly   128 FGSSDRWNGLAIMFDSFDNDNKHNNPYISAVLNDGTKLYDHAEDGTTQLLSGCLRDFRNKPFPTR 192
            |||:|.|||:.|.|||||||.|.|||.|..|.|:|...|||..||.||.|:.|.|||||||:|.|
  Rat   146 FGSADMWNGVGIFFDSFDNDGKKNNPAIVVVGNNGQINYDHQNDGATQALASCQRDFRNKPYPVR 210

  Fly   193 ARIEYYNNVLTVMIHNGMSNNNDDYELCLRADGVNLPKNGYFGISAATGGLADDHDVFHFLTTSL 257
            |:|.||...|||||:||.:.:.:|||.|.:.:.:.:|..|:||||||||||||||||..|||..|
  Rat   211 AKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLTFQL 275

  Fly   258 HAAGQVQEQPKVE----NQEKLTQEYKEYQDKLEKQKQEYKKDHPDEHKDEEDWEEFYESENQRE 318
            ...|:....|:.:    .:||..:|::.:|.:|:|:|:|::|.|||......|  :.:||...||
  Rat   276 TEPGKEPPTPEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAD--DIFESIGDRE 338

  Fly   319 LRQIWQGQSQIADHLRELSRKVDEIIGRQETTLSLVS-----RNAGQALPPPAAGGVPQQQLPVG 378
            |||:::||::|...:::|:|::|.|:..|...:|.::     |.||   .|...|.|.||:|  .
  Rat   339 LRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISRRGAG---TPGQPGQVSQQEL--D 398

  Fly   379 AVSRSDVDLLLTNQNMLLSSIREIRQLVGDINVRTDNIQTNQKHAPTAQIQSTGYDVQTLIAEMR 443
            .|.|:.:: :|...|.:.:|:||..:||..:           :|..:|.:    |:......:::
  Rat   399 TVVRTQLE-ILRQVNEMKNSMRETMRLVSGV-----------QHPGSAGV----YETTQHFMDIK 447

  Fly   444 DGMNQVKQGITHVGQRLAAPQGAAQVANCPT----GNCVGVTLFLSVTVVQLLLVFIYNVFKNRS 504
            :.::.||:.|..:.||   ...:.:...||.    .:|:....|:...|||.:|...|.:::.:.
  Rat   448 EHLHIVKRDIDSLAQR---SMSSNEKPKCPDLPAFPSCLSTVHFVIFIVVQTVLFIGYIMYRTQQ 509

  Fly   505 EAQAKKFY 512
            ||.||||:
  Rat   510 EAAAKKFF 517

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.