DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lk6 and CPK32

DIOPT Version :9

Sequence 1:	NP_651986.2	Gene:	Lk6 / 44672	FlyBaseID:	FBgn0017581	Length:	1142	Species:	Drosophila melanogaster
Sequence 2:	NP_191312.2	Gene:	CPK32 / 824920	AraportID:	AT3G57530	Length:	538	Species:	Arabidopsis thaliana

Alignment Length:	627	Identity:	157/627 - (25%)
Similarity:	217/627 - (34%)	Gaps:	189/627 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 KKRRKKR----ISSSLH-----------------SSTFQEL---YKLTGEILGEGAYASVQTCVN 137
            ||.|||:    |...||                 ..|.:|:   |.| |..||.|.:.....|.:
plant    19 KKGRKKQNPFSIDYGLHHGGGDGGGRPLKLIVLNDPTGREIESKYTL-GRELGRGEFGVTYLCTD 82

  Fly   138 IYTDLEYAVKVIDKIPGHARAR-------VFREVETFHHCQGHLGILQLIEFFEDDEKFYLVFEK 195
            ..||..:|.|.|.|    .:.|       |.||||...|...|..::.|.|.:||:...:||.|.
plant    83 KETDDVFACKSILK----KKLRTAVDIEDVRREVEIMRHMPEHPNVVTLKETYEDEHAVHLVMEL 143

  Fly   196 INGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICD 260
            ..||.|..||.....::|..|:.:.|.|...:...||.|:.||||||||.|........|:|..|
plant   144 CEGGELFDRIVARGHYTERAAAAVTKTIMEVVQVCHKHGVMHRDLKPENFLFGNKKETAPLKAID 208

  Fly   261 FDLG----SGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDKRCDLWSLGVIAY 321
            |.|.    .|.:|...:.||             .:|||||:      ...|....|:||.|||.|
plant   209 FGLSVFFKPGERFNEIVGSP-------------YYMAPEVL------KRNYGPEVDIWSAGVILY 254

  Fly   322 ILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVK 386
            |||||.|||         |...|      :.:.::|......|....|..||:.|||||..:|..
plant   255 ILLCGVPPF---------WAETE------QGVAQAIIRSVLDFRRDPWPKVSENAKDLIRKMLDP 304

  Fly   387 KASNRLSAEAVLNHPWIRMCEQEPPASKHGRRHKALQTPSNIRRNHQSAREISQFAESAMAVKRV 451
            ....||:|:.||:|||::..:..|..|          ....:|...:....:::..:.|:   ||
plant   305 DQKRRLTAQQVLDHPWLQNAKTAPNVS----------LGETVRARLKQFTVMNKLKKRAL---RV 356

  Fly   452 VLQHFSMRYDYMKERPNIYQPSQAYMDAYSDENYNPKPPGHYTRNRSQRNPASSLCGYGGRMSSM 516
            :.:|.                        |||..:....|....:.|||.
plant   357 IAEHL------------------------SDEEASGIREGFQIMDTSQRG--------------- 382

  Fly   517 HGQRANSRRSSRNASRNASAIYPNSGGFKTLNVHEEDDDDEGLEAFGHI--DDD-----DEWSRS 574
                                         .:|:   |:...||:..||.  .||     |.....
plant   383 -----------------------------KINI---DELKIGLQKLGHAIPQDDLQILMDAGDID 415

  Fly   575 RREYQQQCETLGEDRFRRQSGSEGDEVEDDE---------DGENEDYQHYKHYWRELDEEEG--- 627
            |..|....|.:......|:.|       :||         |..|..|...:.....|.:|.|
plant   416 RDGYLDCDEFIAISVHLRKMG-------NDEHLKKAFAFFDQNNNGYIEIEELREALSDELGTSE 473

  Fly   628 ---DDYLYEQQQRVDDKFGEEEFEDEPKEETQADNLKLSKAY 666
               |..:.:.....|.:...|||....|  |..|..|.|:.|
plant   474 EVVDAIIRDVDTDKDGRISYEEFVTMMK--TGTDWRKASRQY 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	100/301 (33%)
Lk6	NP_651986.2	S_TKc	117..403	CDD:214567	99/296 (33%)
CPK32	NP_191312.2	STKc_CAMK	62..320	CDD:270687	98/296 (33%)
CPK32	NP_191312.2	FRQ1	360..501	CDD:227455	35/218 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110