Protein Alignment Lk6 and CAMK2B

DIOPT Version :9

• Sequence 1: NP_651986.2
• Gene: Lk6 / 44672
• FlyBaseID: FBgn0017581
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: XP_011513849.1
• Gene: CAMK2B / 816
• HGNCID: 1461
• Length: 709
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 126/485 - (25%)
• Similarity: 212/485 - (43%)
• Gaps: 98/485 - (20%)

  Fly   104 ISSSLHSSTFQELYKLTGEILGEGAYASVQTCVNIYTDLEYAVKVID--KIPGHARARVFREVET 166
            :::::..:.|.:.|:|. |.:|:||::.|:.||.:.|..|||.|:|:  |:......::.||...
Human     1 MATTVTCTRFTDEYQLY-EDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARI 64

  Fly   167 FHHCQ--GHLGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDF 229
               |:  .|..|::|.:...::...||||:.:.||.|...|.....:||.:||..|::|...:..
Human    65 ---CRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLH 126

  Fly   230 LHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISS---PAATPQLLTPVGSAEF 291
            .|:.|:.||||||||:|.........:|:.||  |..|:...|..:   .|.||         .:
Human   127 CHQMGVVHRDLKPENLLLASKCKGAAVKLADF--GLAIEVQGDQQAWFGFAGTP---------GY 180

  Fly   292 MAPEVVDLFVGEAHYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFES 356
            ::|||:     ....|.|..|:|:.|||.||||.|||||         |:..      |..|::.
Human   181 LSPEVL-----RKEAYGKPVDIWACGVILYILLVGYPPF---------WDED------QHKLYQQ 225

  Fly   357 IQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWIRMCEQEPPAS-KHGRRHK 420
            |:.|.:.||..||..|:.|||:||:.:|....:.|::|...|.|||:  |::...|| .|.:...
Human   226 IKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWV--CQRSTVASMMHRQETV 288

  Fly   421 ALQTPSNIRRNHQSAREISQFAESAMAVKRVVLQHFSMRYDYMKERPNIYQPSQAYMDAYSDENY 485
            ......|.||.          .:.|:....:..::||:
Human   289 ECLKKFNARRK----------LKGAILTTMLATRNFSV--------------------------- 316

  Fly   486 NPKPPGHYTRNRSQRNPASS--LCGYGGRMSSMHGQRANSRRSSRNASRNASAIYPNSGGF---- 544
                 |..|...:..:.|:|  ..|...:..|:..::|:..:...|:::|::|.....|..
Human   317 -----GRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAA 376

  Fly   545 ---KTLNVHEEDD--DDEGLEAFGHIDDDD 569
               :|..:|...|  .:....|...|:|:|
Human   377 LEPQTTVIHNPVDGIKESSDSANTTIEDED 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	96/294 (33%)
		S_TKc	117..403	CDD:214567	96/292 (33%)
CAMK2B	XP_011513849.1	STKc_CaMKII	12..303	CDD:270988	104/337 (31%)
		S_TKc	14..272	CDD:214567	96/292 (33%)
		CaMKII_AD	577..704	CDD:285524

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920