Protein Alignment Lk6 and STK33

DIOPT Version :9

• Sequence 1: NP_651986.2
• Gene: Lk6 / 44672
• FlyBaseID: FBgn0017581
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_001275990.1
• Gene: STK33 / 65975
• HGNCID: 14568
• Length: 514
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 138/572 - (24%)
• Similarity: 237/572 - (41%)
• Gaps: 128/572 - (22%)

  Fly    31 DSGIRSGSGISCSNTDNSCSQSQSDGQNELTRYSSE----------DVSGNES-SEAPNMTEVER 84
            |||:...|        ..|....|..|.::....|.          ::|...| ..|.::..:||
Human     3 DSGLDKKS--------TKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLER 59

  Fly    85 QAELNRHKEEMQKKRRKKRISS------------------------SLHSSTFQELYKLTGEILG 125
            :.|.|.:::...:|....|.|:                        ..:.:..:|:|.. |.|||
Human    60 KKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTF-GRILG 123

  Fly   126 EGAYASVQTCVNIYTDLEYAVKVIDK-IPGHARARVF-REVETFHHCQGHLGILQLIEFFEDDEK 188
            :|::..|....:..|:.::|:|.::| ..|.:..::. |||......: |..|:.|.:.||..:|
Human   124 KGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK-HEHIIHLEQVFETPKK 187

  Fly   189 FYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSL 253
            .|||.|....|.|...:.....|||:|...||:.:||.:.:||...|.|||||.|||: ||:..:
Human   188 MYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIM-VKSSLI 251

  Fly   254 -------CPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDKRC 311
                   ..||:.||  |..:|     ....:...|....|:..:|||||:     .||.|.::|
Human   252 DDNNEINLNIKVTDF--GLAVK-----KQSRSEAMLQATCGTPIYMAPEVI-----SAHDYSQQC 304

  Fly   312 DLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEA 376
            |:||:||:.|:||.|.|||               ..:.:|.|||.|::|...|..|.|:.:||.|
Human   305 DIWSIGVVMYMLLRGEPPF---------------LASSEEKLFELIRKGELHFENAVWNSISDCA 354

  Fly   377 KDLISNLLVKKASNRLSAEAVLNHPWIRMCEQEPPASKHGRRHKALQTPSNI-------RRNHQS 434
            |.::..|:....::|::|:.:|::.|:.           |.:..::: |:|:       :.|.:|
Human   355 KSVLKQLMKVDPAHRITAKELLDNQWLT-----------GNKLSSVR-PTNVLEMMKEWKNNPES 407

  Fly   435 AREISQFAESAMAVKRVVLQHFSMRYDYMKERPNIYQPSQAYMDA-YSDENYNPKPPGHYTRNRS 498
            ..|.:...::..:.               :|:...|||.....|| |:.:....|....|    .
Human   408 VEENTTEEKNKPST---------------EEKLKSYQPWGNVPDANYTSDEEEEKQSTAY----E 453

  Fly   499 QRNPASSLCGYGGRMSSMHGQ-------RANSRRSSRNASRNASAIYPNSGG 543
            ::.||:|...:....||....       :....::....|:..:..||...|
Human   454 KQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSG 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	95/296 (32%)
		S_TKc	117..403	CDD:214567	94/294 (32%)
STK33	NP_001275990.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..91		3/25 (12%)
		STKc_STK33	114..381	CDD:270999	95/296 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	402..468		15/84 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	485..514		4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010