Protein Alignment Lk6 and dclk2a

DIOPT Version :9

• Sequence 1: NP_651986.2
• Gene: Lk6 / 44672
• FlyBaseID: FBgn0017581
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_001128593.1
• Gene: dclk2a / 572548
• ZFINID: ZDB-GENE-050420-170
• Length: 810
• Species: Danio rerio
• Alignment Length: 568
• Identity: 157/568 - (27%)
• Similarity: 257/568 - (45%)
• Gaps: 97/568 - (17%)

  Fly     5 KSGTAASAAAAKASNNNNNNHP-----RGSGDSGIRSGSGISCSNTDNSCSQSQSDGQNELTRYS 64
            :|.:..||.......:.|:..|     .|:.:|.|.:......|::..:..:|..:.:......|
Zfish   319 RSKSPGSARRTAGHFSTNSQSPVKSPINGAPNSQITTPKSAKSSSSSPTSPRSMRNFKIPTHHSS 383

  Fly    65 SEDVSGNESSEAPNMTEVERQAELNRHKEEMQKKRRKKRISSSLHSSTFQELYKLTGEILGEGAY 129
            :.:|:|  |||.|.........|:|.::              :|.:||..:.||: |:::|:|.:
Zfish   384 AGNVNG--SSETPQHHNNSLSPEVNGNR--------------NLAASTILDKYKI-GKVIGDGNF 431

  Fly   130 ASVQTCVNIYTDLEYAVKVIDKIPGHARARVF-REVETFHHCQGHLGILQLIEFFEDDEKFYLVF 193
            |.|:.||...|..|:|:|:|||.....:..:. .||......: |..|:.|||..:...:.|||.
Zfish   432 AVVKECVERSTGKEFALKIIDKNKCRGKEHLIENEVAVLRRVK-HPNIIMLIEEVDTPAELYLVM 495

  Fly   194 EKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENIL-CVKTDSLCPIK 257
            |.:.||.|...|.....::|.:||.::.::|:.|.:||:..|.|||:||||:| |...:....:|
Zfish   496 ELVKGGDLFDAITSSTKYTEKDASVMVFDLAAALKYLHRMCIVHRDIKPENLLVCEYPNGTKSLK 560

  Fly   258 ICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDKRCDLWSLGVIAYI 322
            :.||.|      .|.:..|     |.|..|:..::|||:    :.|:. |..:.|:|:.|||.||
Zfish   561 LGDFGL------ATVVEGP-----LYTVCGTPTYVAPEI----IAESG-YGLKVDIWAAGVITYI 609

  Fly   323 LLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVKK 387
            ||||:|||           |.||  ..||.||:.|..||..||...|.::||.||:||.::|...
Zfish   610 LLCGFPPF-----------RSEN--NLQEDLFDQILLGHLEFPSPFWDNISDSAKELIGHMLQVN 661

  Fly   388 ASNRLSAEAVLNHPWIRMCEQEPPASKHGRRHKALQTPSNIRRNHQSARE-------ISQFAESA 445
            ...|.:||.||:|||:    .|..|.::..:   ::....::::..|.::       :|....:|
Zfish   662 VEARYTAEDVLSHPWV----TEDAAMENNMK---MEVAGKLKKHFNSVQKQSNTSAGVSVIMNTA 719

  Fly   446 MAVKRVVLQHFSMRYDYMKERPNIYQPSQAYMDAYSDENYNPKPPGHYTRNRSQRNPASSLCGYG 510
            :..:.:.|.|  .|.|....||. .:||..          ||:      |.||.|..:|
Zfish   720 LDKETIQLSH--RRQDRNPPRPE-KRPSST----------NPE------RRRSNRGRSS------ 759

  Fly   511 GRMSSMHGQRANSRRSSRNASRNASAIYPN--SGGFKTLNVHEEDDDD 556
              :.|...:.|.....:.:|:.:|.|..|:  |..|...|...|...|
Zfish   760 --VQSEDSRSAAPIEPATSANPSAPAALPSDPSPQFHECNTESEASKD 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	103/289 (36%)
		S_TKc	117..403	CDD:214567	103/287 (36%)
dclk2a	NP_001128593.1	DCX	59..149	CDD:214711
		DCX	186..274	CDD:214711
		STKc_DCKL2	418..676	CDD:271086	102/288 (35%)
		S_TKc	420..677	CDD:214567	103/287 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010