Protein Alignment Lk6 and PHKG2

DIOPT Version :9

• Sequence 1: NP_651986.2
• Gene: Lk6 / 44672
• FlyBaseID: FBgn0017581
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_000285.1
• Gene: PHKG2 / 5261
• HGNCID: 8931
• Length: 406
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 114/395 - (28%)
• Similarity: 169/395 - (42%)
• Gaps: 62/395 - (15%)

  Fly   122 EILGEGAYASVQTCVNIYTDLEYAVKVIDKIP--------GHARARVFREVETFHHCQGHLGILQ 178
            :::|.|..:.|:.||:..|..|:|||:::...        ...|....||........||..|:.
Human    28 DVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIIT 92

  Fly   179 LIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPE 243
            ||:.:|.....:|||:.:..|.|...:.|.:..||.|...|::.:...:.|||...|.|||||||
Human    93 LIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPE 157

  Fly   244 NILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAH-YY 307
            |||   .|....|::.||.....::....:.....||         .::|||::...:.|.| .|
Human   158 NIL---LDDNMQIRLSDFGFSCHLEPGEKLRELCGTP---------GYLAPEILKCSMDETHPGY 210

  Fly   308 DKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDV 372
            .|..|||:.|||.:.||.|.|||         |:|.      |.|:...|.||.:.|...||.|.
Human   211 GKEVDLWACGVILFTLLAGSPPF---------WHRR------QILMLRMIMEGQYQFSSPEWDDR 260

  Fly   373 SDEAKDLISNLLVKKASNRLSAEAVLNHPWIRMCEQEPPASKHGRRHKALQTPSNIRRNHQSARE 437
            |...|||||.||......||:||..|.||:...||...|.:         .||   |:..:.|
Human   261 SSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWN---------LTP---RQRFRVA-- 311

  Fly   438 ISQFAESAMAVKRVVLQHFSMR---YDYMKERPNIYQPSQAYMDAYSDENYNPKPPGHYTRNRSQ 499
                ..:.:|..||.|....:|   .:.:...|...:..:..:|..:...|     ||:.:...|
Human   312 ----VWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLY-----GHWVKKGEQ 367

  Fly   500 RNPAS 504
            :|.|:
Human   368 QNRAA 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	94/289 (33%)
		S_TKc	117..403	CDD:214567	94/289 (33%)
PHKG2	NP_000285.1	STKc_PhKG2	13..291	CDD:271083	94/289 (33%)
		Calmodulin-binding (domain-N). /evidence=ECO:0000250	306..330		5/29 (17%)
		Calmodulin-binding (domain-C). /evidence=ECO:0000250	346..370		5/28 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920