DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lk6 and CG17528

DIOPT Version :9

Sequence 1:	NP_651986.2	Gene:	Lk6 / 44672	FlyBaseID:	FBgn0017581	Length:	1142	Species:	Drosophila melanogaster
Sequence 2:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	105/341 - (30%)
Similarity:	167/341 - (48%)	Gaps:	70/341 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 EVERQAELNRHKEEMQKKRRKKRISSSLHSSTFQELYKL---------TGEILGEGAYASVQTCV 136
            :.|...|.:||              ::|.:||..|:.:|         .|.|:|:|.:|.|....
  Fly   445 KAETTPEDDRH--------------AALLTSTGMEINELPSNIRNTYSLGRIIGDGNFAIVFKIK 495

  Fly   137 NIYTDLEYAVKVID--KIPG-----HARARVFREVETFHHCQGHLGILQLIEFFEDDEKFYLVFE 194
            :..|...||:|:||  |..|     .|..||.:::       .|..|:.||...:.:...|||.|
  Fly   496 HRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKL-------NHPHIISLILSVDQNTNMYLVLE 553

  Fly   195 KINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTD---SLCPI 256
            .::||.|...|.:...|||:::..:|:.:.:.:.:||..||.|||:||||:| ||.|   ::..:
  Fly   554 YVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLL-VKLDEHGNVLEL 617

  Fly   257 KICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDKRCDLWSLGVIAY 321
            |:.||.|...:   .|:        |....|:..::|||:: |.||    |..:.|:|:.|:|.|
  Fly   618 KLADFGLACEV---NDL--------LYAVCGTPTYVAPEIL-LEVG----YGLKIDVWAAGIILY 666

  Fly   322 ILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVK 386
            |||||:|||.....:             ||.||::|..|.:.||:..|.|:.|..:|||:|:|..
  Fly   667 ILLCGFPPFVAPDNQ-------------QEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQA 718

  Fly   387 KASNRLSAEAVLNHPW 402
            ....|.::|.:|:|.|
  Fly   719 DPDVRFTSEDILDHSW 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	98/307 (32%)
Lk6	NP_651986.2	S_TKc	117..403	CDD:214567	97/305 (32%)
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	95/293 (32%)
		S_TKc	477..734	CDD:214567	95/293 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466843
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24349
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040