Protein Alignment Lk6 and mlck-1

DIOPT Version :9

• Sequence 1: NP_651986.2
• Gene: Lk6 / 44672
• FlyBaseID: FBgn0017581
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_509689.1
• Gene: mlck-1 / 181217
• WormBaseID: WBGene00013869
• Length: 1211
• Species: Caenorhabditis elegans
• Alignment Length: 1037
• Identity: 232/1037 - (22%)
• Similarity: 392/1037 - (37%)
• Gaps: 286/1037 - (27%)

  Fly   102 KRISSSLHSSTFQELYKLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKIPGHA-RARVFREVE 165
            |:|.:...:..|..||::| ::||:|.:..|...:...|..|:|.|.| ||...| ||.|.|||.
 Worm    30 KKIENIRANVKFDTLYQVT-KLLGDGKFGKVYCVIEKETGKEFAAKFI-KIRKEADRAEVEREVS 92

  Fly   166 TFHHCQGHLGILQLIE-FFEDDEKFYLVFEKINGGPLLSRI-QEHICFSEHEASQIIKEIASGLD 228
            .....: |..|.|:.: |:.......|:.|.:.||.|..|: :|....||.....||.::...:|
 Worm    93 ILTQLR-HPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESYVLSELAVVMIICQLCEAID 156

  Fly   229 FLHKKGIAHRDLKPENILCVKTDSLC--PIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEF 291
            ::||:.|.|.|:|||||:||   ||.  .||:.||.|......|.::...|.||         ||
 Worm   157 YIHKQNILHLDVKPENIMCV---SLTGNRIKLIDFGLARHYDGTQELKYMAGTP---------EF 209

  Fly   292 MAPEVVDLFVGEAHYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFES 356
            .||||:     :....|...|:||:|||.||||.||.||.|:       |.||.        :.:
 Worm   210 AAPEVI-----KFEKLDYHTDMWSIGVITYILLSGYSPFLGD-------NLGET--------YCN 254

  Fly   357 IQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWIRMCEQEPPASKHGRR--- 418
            :::|.:.|.| |:..|::||||.::.|||...|.|:.....|.||||         :||.::
 Worm   255 VEKGVWEFTE-EFDTVTEEAKDFVTKLLVYDQSKRMLPHECLQHPWI---------AKHRQKAAC 309

  Fly   419 ----HKALQTPS---------NIRR-----------------------------NHQSAREISQF 441
                .|.|..|:         |.||                             .|:....:.:.
 Worm   310 NTILEKPLNAPTLDNKQIMRYNARRKFRRMIIYVKFLIEMNRLRNSLKTRMSANGHKFFDPLLKM 374

  Fly   442 AES---------------AMAVKRVVLQHFSMRYDYMKERPNIYQPSQAYMDAYSDENYNPKPPG 491
            ||.               |..:..:|    .|..|..|:..::        ....|.|.:.:|
 Worm   375 AEKKEQKISNAIGTAGCPASGLGSLV----KMAVDSQKKNGDV--------PVTQDANMSTEP-- 425

  Fly   492 HYTRNRSQRNPASSLCGYGG-----RMSSMH-----------GQRANSRRSSRNASRNASAIYP- 539
                .:.::.....:....|     :.||:.           |.|......::.||....::..
 Worm   426 ----EKEEKKKKKKIANADGSTKTEKTSSVKKKKLVETDGDAGLRPPPELMTKRASTGGESLLAA 486

  Fly   540 -------------NSGGFKTL-NVHEEDD-----DDEGLEAFGHIDDDDEWSRSRREYQ------ 579
                         ||...|:| :|.||.:     ..||.:.....::.|...:|....|
 Worm   487 VKVLKNLEVVENGNSPKRKSLCSVKEEKEIPAKKQTEGYKTLETTENGDIRRKSAPVKQDTLTCQ 551

  Fly   580 -------QQCETLGEDRFRRQSGSEGDE--VEDDEDGENEDYQHYKHYWRELDEEEGDDYLYEQQ 635
                   |..||......||:|.|..:|  |:.:|....:.....|.  .:..|........|:.
 Worm   552 DNSKVTPQLLETAPNGEIRRKSASAKEEKSVKPEEVIRKKSSASVKE--TKTVELSVVPVKLEKL 614

  Fly   636 QRVDDKFGEEEFEDEPKEETQADNLKLSKAYVEQVGETNVEKSKPQDDNGGYIREDLIMDNMDMK 700
            ..:|:| ||:..:.:.|..|....::..|:.:|...|..|||.|       .:...|:.|.::.:
 Worm   615 ASIDEK-GEKLVKKKKKTTTVTAEIEKPKSVIESKEEKLVEKPK-------LLNGTLVSDALEKR 671

  Fly   701 KN--------TQQ--------SEFAKLTIMRNDAQTEENKIM---------------QQQDEEKK 734
            ::        ||.        .:|:...::.:..:.:|:|..               .:|...:|
 Worm   672 RSLGSKRASETQDVGLRPLPVVDFSPKIVLTDKKEPKESKTKPAEPLKEIVPETKKPARQGALRK 736

  Fly   735 EEKQQDDVDGAKKQGPS-SDISATTITDNNKLQTPVMTTTHINNWQTGDAIEDDDV----KLLDS 794
            .:|..||:..|   .|| :.:|.:|:|   .::..|:.|.|    .:|:.|:.:.|    |.|..
 Worm   737 RDKSLDDILNA---APSPTTLSKSTVT---SVKHSVVETIH----PSGEIIKSEKVLTKKKSLKK 791

  Fly   795 ISDLNEKLPEIYETANIVVNSAAVPAASTPAASATRPPTDN--------PEE-----DDSNVTKP 846
            ...::::||     ..|:.:.|::|...|...:....|...        ||:     |:...||.
 Worm   792 DKSIDDRLP-----VKIIEDKASLPKLKTDVVTFESKPVKKTSKIVKLIPEDANLIKDEKKPTKI 851

  Fly   847 TTTAE---GTTMQTTFGM---SAEEEKPVALSHTAGHHSKTGRTVNFAPDAYQNDEDADIDEDDD 905
            ..|:|   .||:|||..:   :...||.|       .|:..|::|..:.......:|..:.:...
 Worm   852 VMTSEKQATTTVQTTTSVKRTTKSSEKKV-------EHTADGKSVESSQKKNSQKDDVKVSQVTT 909

  Fly   906 YDDEENLHEHSKQQLPSNAYTRKQRQQHQRYIVPRYQLADQVPQRQHTENWRYRTHHSQEQQ 967
            ..:|:     |.|..|:              :..:..:..|..::..:|. .::|..::||:
 Worm   910 KKEED-----STQPAPT--------------LTVKKNVVKQTAEKSTSEK-EHKTTENKEQE 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	102/292 (35%)
		S_TKc	117..403	CDD:214567	101/290 (35%)
mlck-1	NP_509689.1	PKc_like	51..300	CDD:389743	99/283 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000