DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lk6 and Camk2g

DIOPT Version :9

Sequence 1:	NP_651986.2	Gene:	Lk6 / 44672	FlyBaseID:	FBgn0017581	Length:	1142	Species:	Drosophila melanogaster
Sequence 2:	XP_008768708.1	Gene:	Camk2g / 171140	RGDID:	621802	Length:	588	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	124/467 - (26%)
Similarity:	196/467 - (41%)	Gaps:	86/467 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 FQELYKLTGEILGEGAYASVQTCVNIYTDLEYAVKVID--KIPGHARARVFREVETFHHCQ--GH 173
            |.:.|:|..| ||:||::.|:.||...:..|||.|:|:  |:......::.||...   |:  .|
  Rat    10 FTDDYQLFEE-LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARI---CRLLKH 70

  Fly   174 LGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIAHR 238
            ..|::|.:...::...||||:.:.||.|...|.....:||.:||..|.:|...::.:|:..|.||
  Rat    71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHR 135

  Fly   239 DLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGE 303
            ||||||:|.........:|:.||.|.        |.............|:..:::|||:     .
  Rat   136 DLKPENLLLASKCKGAAVKLADFGLA--------IEVQGEQQAWFGFAGTPGYLSPEVL-----R 187

  Fly   304 AHYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAE 368
            ...|.|..|:|:.|||.||||.|||||         |:..      |..|::.|:.|.:.||..|
  Rat   188 KDPYGKPVDIWACGVILYILLVGYPPF---------WDED------QHKLYQQIKAGAYDFPSPE 237

  Fly   369 WHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWIRMCEQEPPAS------------KHGRRHK- 420
            |..|:.|||:||:.:|....:.|::|:..|.|||:  |::...||            |...|.|
  Rat   238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWV--CQRSTVASMMHRQETVECLRKFNARRKL 300

  Fly   421 --ALQTPSNIRRNHQSAREISQFAESAMAVKRVVLQHFSMRYDYMKERPNIYQPSQAYMDAYSDE 483
              |:.|...:.||....|:.|..|..|.:...:.                 .|.:::.::..||.
  Rat   301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLA-----------------GQAAKSLLNKKSDG 348

  Fly   484 NYNPKPPGHYTRNRSQRNPASSLCGYGGRMSSMHGQRANSRRSSRNASRNASAIYPNS-----GG 543
            ....:..........|.|..:||.           ..|......:.|....:.:..|:     |.
  Rat   349 GVKKRKSSSSVHLMPQSNNKNSLV-----------SPAQEPAPLQTAMEPQTTVVHNATDGIKGS 402

  Fly   544 FKTLNVHEEDDD 555
            .::.|...||:|
  Rat   403 TESCNTTTEDED 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	93/291 (32%)
Lk6	NP_651986.2	S_TKc	117..403	CDD:214567	93/289 (32%)
Camk2g	XP_008768708.1	STKc_CaMKII	12..303	CDD:270988	100/324 (31%)
Camk2g	XP_008768708.1	CaMKII_AD	456..583	CDD:285524
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010