Protein Alignment Lk6 and Lk6

DIOPT Version :10

• Sequence 1: NP_651986.2
• Gene: Lk6 / 44672
• FlyBaseID: FBgn0017581
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: XP_061499880.1
• Gene: Lk6 / 1273831
• VectorBaseID: AGAMI1_000391
• Length: 1482
• Species: Anopheles gambiae
• Alignment Length: 1342
• Identity: 491/1342 - (36%)
• Similarity: 628/1342 - (46%)
• Gaps: 395/1342 - (29%)

  Fly    49 CSQSQSD--GQNELTRYSSEDVSGNESSEAPNMTEVERQAELNRHKEEM-QKKRRKKRISSSLHS 110
            |....||  .:.::.|||||:||||||:||..::|.||||:.||||||| :|:|||||.|||:.|
Mosquito     9 CCDVNSDPTRKTDVARYSSEEVSGNESTEARMLSEAERQADFNRHKEEMKRKRRRKKRTSSSMQS 73

  Fly   111 STFQELYKLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKIPGHARARVFREVETFHHCQGHLG 175
            |.||||||||||:||||||||||||:||||:||||||:|||||||||.|||||||||||||||..
Mosquito    74 SCFQELYKLTGEVLGEGAYASVQTCINIYTELEYAVKIIDKIPGHARGRVFREVETFHHCQGHPN 138

  Fly   176 ILQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDL 240
            ||||:||||||||||||||||||||||:||||::||||::|:|||||||||||||||||||||||
Mosquito   139 ILQLLEFFEDDEKFYLVFEKINGGPLLTRIQENVCFSEYDAAQIIKEIASGLDFLHKKGIAHRDL 203

  Fly   241 KPENILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAH 305
            ||||||||..|.|||||||||||||||||||:||||.||||||||||||||||||||||||||::
Mosquito   204 KPENILCVYPDKLCPIKICDFDLGSGIKFTTNISSPNATPQLLTPVGSAEFMAPEVVDLFVGESN 268

  Fly   306 YYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWH 370
            |||||||||||||||||||||||||||||.:||||||||||||||||||||||||.:.||::||.
Mosquito   269 YYDKRCDLWSLGVIAYILLCGYPPFSGNCEQDCGWNRGENCRTCQELLFESIQEGRYCFPDSEWQ 333

  Fly   371 DVSDEAKDLISNLLVKKASNRLSAEAVLNHPWIRMCEQ--------EPPASKHGRRHKALQTPSN 427
            |||:||||||..||||:|..||||.|||||||||:.:.        ...|:|..:|.:.|:||..
Mosquito   334 DVSEEAKDLIRGLLVKEAPKRLSATAVLNHPWIRISDDTECAVGGINSKANKEKQRRRVLKTPGV 398

  Fly   428 IRRNHQSAREISQFAESAMAVKRVVLQHFSMRYDYM-KERPNIYQPS------------QAYMDA 479
            |||| |||.|:|.|||||||||||::|||||||||| ||||||||||            :..:..
Mosquito   399 IRRN-QSALELSHFAESAMAVKRVIMQHFSMRYDYMAKERPNIYQPSYNGSVEPAAKPTETVLPT 462

  Fly   480 YSDENYNPKPPGHYTRNRSQRNPASSLCGYGGRMSSMHGQRANSRRSSRNASRNASAIYPNSGGF 544
            ...|..|.:||                               ||..||.::|.......|.:.
Mosquito   463 LVVETGNAQPP-------------------------------NSSSSSSSSSGVVKPFVPRTE-- 494

  Fly   545 KTLNVHEED----DDDEGL----EAFGHIDDDDEWSRSRRE--------YQQ---QCETLGEDRF 590
            :...|.:||    :.|||:    ....|::...||.:...|        ||.   ..:.:|....
Mosquito   495 EPNGVCDEDELCKERDEGMGMQPMTTNHVETGKEWEKDEEEQKELIRGSYQNVSIDSQNMGAAAA 559

  Fly   591 --------------------------------RRQSGSEGD------EVEDDEDGENEDYQHYKH 617
                                            ...||||||      .:.....|.:|
Mosquito   560 TGVKVPTITIASVAAGNADVAVGAATIEIVVNSTSSGSEGDCTFSSNTIAAGRSGSDE------- 617

  Fly   618 YWRELDEEEGDDYLYEQQQRVDDKFGEEEFEDEPKEETQADNLKLSKAYVEQVGETNVEKSKPQD 682
                             :..:....||.|.:|.|::|..:|.              .::.|.|..
Mosquito   618 -----------------RGSIVGSGGEAERKDFPQQENTSDK--------------ELQSSDPPK 651

  Fly   683 DN--GGYIREDLIMDNMDMKKNTQQSEFAKLTIMRNDAQTEENKIMQQQDEEKKEEKQQDDVDGA 745
            :|  ||..|:|             |.:.:.||..:..|:...::..:::.|:.||...:.....:
Mosquito   652 NNAAGGGARDD-------------QDDDSVLTGGKAVAEARADEAREKELEKAKEVVVELSPQSS 703

  Fly   746 KKQGPSSDISATTITDNNKLQTPVMTTTHINNWQ-TGDAIEDDDVKLLDSISDLNEKLPEIYETA 809
            ....|...|..:..|...:..:........:||: .|:             ...:::.|..||..
Mosquito   704 TLSSPVRSIVGSKATGGPRKASNGWDIPPESNWRYRGE-------------QQQHQQSPSSYEYN 755

  Fly   810 NIVVNSAAVPAASTPAASATRPPT-----DNPEEDD------SNV--------------TKPTTT 849
            :...::......|:...|:.:...     .:|:...      :||              :.|..:
Mosquito   756 SRSQHAHGYKYGSSGFGSSYKGGRSGHYHSHPQHHQHHHHHHNNVHYSNYHHHHSSNHHSHPPMS 820

  Fly   850 AEGTTMQTTFGMSAEEEKPVALSHTAGHHSKTGRTVNF------APDAYQNDEDADIDEDDDYDD 908
            :.|:..|.. |.....    |.|| .||:..:....|:      || .|.....|....::.:|.
Mosquito   821 STGSYRQQN-GSGHHH----AGSH-GGHYGNSHGNHNYSNGSSIAP-RYGRIVRAGATSNEPFDG 878

  Fly   909 --EENLHEHSKQQLPSNAYTRKQRQQHQRYIVPRYQLADQVPQRQHTEN-------------WRY 958
              |......:|||    .::.:|:|||..|              .|..|             ||.
Mosquito   879 GFEGRSGMMAKQQ----RHSSQQQQQHYPY--------------SHHPNHGSSSSSSASLTSWRA 925

  Fly   959 R--------THHSQEQQPTAD----YRKY----RPPFSTGGGGG--------HHGNQQ------- 992
            :        .|...:...|.|    |.:|    ....|.|||||        |:||.:
Mosquito   926 QPSPAYGSNQHRYGDAAGTGDEAETYHRYHNGNNNSSSNGGGGGGMLTASQSHYGNGKITTNPNN 990

  Fly   993 ---------------RNYLGSFSHSGGAAGYKIAPMPPPM-------QPPPRH------------ 1023
                           .|...|.|.|||::.:     |..|       .|...|
Mosquito   991 FNHHQYNRGGTNNNVNNNTSSVSSSGGSSHH-----PARMNGGNTSGHPSQYHHQQQQQQQQQQQ 1050

  Fly  1024 -------------NSAGS-----SGSGSGSGGSPPSDEQSAIRNWRQDCVYARSCGMNQGPEQQ- 1069
                         |:.||     :|:|.|..|.......|:..|      :....|...|.:||
Mosquito  1051 QQNHQYHHYAGVNNNNGSNHYYHNGTGRGGDGGGMGHYNSSNNN------HHYGAGNGHGGQQQQ 1109

  Fly  1070 ----------RHNRSSGQRVQQQPRIGSGRFAHLQ---------------------------AAQ 1097
                      :|:....|:.|.|.......:..::                           |.|
Mosquito  1110 KSMPYRAVVVQHHHQQHQQYQNQRYASPSSYGGMRRPTQSLMIDAVDGAGMKGAAAGPRRASAGQ 1174

  Fly  1098 LMDELPDMRIGLSPPSESVLLQRRLRQQQRANDLSEYCEPAT 1139
            ....||..|  .|||.:|        |||:.:..:..|:|.|
Mosquito  1175 QQSSLPMQR--ASPPQQS--------QQQQQSRSNVNCDPTT 1206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	251/287 (87%)
Lk6	XP_061499880.1	None