Protein Alignment Lk6 and Camk2d

DIOPT Version :9

• Sequence 1: NP_651986.2
• Gene: Lk6 / 44672
• FlyBaseID: FBgn0017581
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_001333564.1
• Gene: Camk2d / 108058
• MGIID: 1341265
• Length: 533
• Species: Mus musculus
• Alignment Length: 636
• Identity: 156/636 - (24%)
• Similarity: 251/636 - (39%)
• Gaps: 152/636 - (23%)

  Fly   104 ISSSLHSSTFQELYKLTGEILGEGAYASVQTCVNIYTDLEYAVKVID--KIPGHARARVFREVET 166
            ::|:...:.|.:.|:|..| ||:||::.|:.|:.|.|..|||.|:|:  |:......::.||...
Mouse     1 MASTTTCTRFTDEYQLFEE-LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARI 64

  Fly   167 FHHCQ--GHLGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDF 229
               |:  .|..|::|.:...::...||||:.:.||.|...|.....:||.:||..|::|...::.
Mouse    65 ---CRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNH 126

  Fly   230 LHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISS---PAATPQLLTPVGSAEF 291
            .|..||.||||||||:|.........:|:.||  |..|:...|..:   .|.||         .:
Mouse   127 CHLNGIVHRDLKPENLLLASKSKGAAVKLADF--GLAIEVQGDQQAWFGFAGTP---------GY 180

  Fly   292 MAPEVVDLFVGEAHYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFES 356
            ::|||:     ....|.|..|:|:.|||.||||.|||||         |:..      |..|::.
Mouse   181 LSPEVL-----RKDPYGKPVDMWACGVILYILLVGYPPF---------WDED------QHRLYQQ 225

  Fly   357 IQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWIRMCEQEPPASKHGRRHKA 421
            |:.|.:.||..||..|:.||||||:.:|....:.|::|...|.||||  |::...||...|
Mouse   226 IKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI--CQRSTVASMMHR---- 284

  Fly   422 LQTPSNIRRNHQSAREISQFAESAMAVKRVVLQHFSMRYDYMKERPNIYQPSQAYMDAYSDENYN 486
             |...:..:...:.|::    :.|:....:..::||.....:|:...:...::|.:.....||.
Mouse   285 -QETVDCLKKFNARRKL----KGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENI- 343

  Fly   487 PKPPGHYTRNRSQRNPASSLCGYGGRMSSMHGQRANSRRSSRNASRNASAIYPNSGGFKTLNVHE 551
            |.|                                              |:.|     :|..:|.
Mouse   344 PTP----------------------------------------------ALEP-----QTTVIHN 357

  Fly   552 EDDDDEGLEAFGHIDDDDEWSRSRREYQQQCETLGEDRFRRQSGSEGDEVEDDEDGENEDYQHYK 616
            .|.:.|..|:.....:|::....::|..:..|.|               :|...:|:.|.|....
Mouse   358 PDGNKESTESSNTTIEDEDVKARKQEIIKVTEQL---------------IEAINNGDFEAYTKIC 407

  Fly   617 HYWRELDEEEGDDYLYEQQQRVDDKFGEEEFEDEPKEETQADNLKLSKAYVEQVGETNVEKSKPQ 681
            .......|.|....|.|...     |....||:...:..:..:..:...:|..||
Mouse   408 DPGLTAFEPEALGNLVEGMD-----FHRFYFENALSKSNKPIHTIILNPHVHLVG---------- 457

  Fly   682 DDNG--GYIREDLIMDNMDMKKNTQQSEFAKLTIMRNDAQTEENKIMQQQD 730
            ||..  .|||....||...|.|.               .|:||.::..::|
Mouse   458 DDAACIAYIRLTQYMDGSGMPKT---------------MQSEETRVWHRRD 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lk6	NP_651986.2	STKc_Mnk	115..403	CDD:270992	99/294 (34%)
		S_TKc	117..403	CDD:214567	99/292 (34%)
Camk2d	NP_001333564.1	STKc_CaMKII	12..303	CDD:270988	107/336 (32%)
		CaMKII_AD	380..507	CDD:285524	30/159 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920