Protein Alignment cwo and HES4

DIOPT Version :9

• Sequence 1: NP_524775.1
• Gene: cwo / 44669
• FlyBaseID: FBgn0259938
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001135939.1
• Gene: HES4 / 57801
• HGNCID: 24149
• Length: 247
• Species: Homo sapiens
• Alignment Length: 171
• Identity: 52/171 - (30%)
• Similarity: 76/171 - (44%)
• Gaps: 27/171 - (15%)

  Fly    52 ATGRRNKTSRQ---DPLSHR-IIEKRRRDRMNSCLADLSRLIPPQYQRKG--RGRIEKTEIIEMA 110
            |||.|.....|   ||.|.: ::|||||.|:|..||.|..||....:::.  ..::||.:|:||.
Human    46 ATGGREGRGTQPVPDPQSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMT 110

  Fly   111 IRHLKHLQ--------SECQQKESDYRSGYMDCMKEAAKFLYDVH--MQDFCHRLLGRLQEHIDE 165
            :|||:.|:        |........||:|:.:|:.|..:||....  ..|...||||.|
Human   111 VRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHL------ 169

  Fly   166 MFKTDCYKSTRSCHMPDNVSASSGSPHQAYHPPLCHLRDML 206
               ..|.:.......|  .|.|..:|.:|..|.:...|.:|
Human   170 ---AACLRQLGPSRRP--ASLSPAAPAEAPAPEVYAGRPLL 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cwo	NP_524775.1	HLH	66..118	CDD:306515	21/54 (39%)
		ORANGE	126..168	CDD:128787	13/43 (30%)
HES4	NP_001135939.1	HLH	62..119	CDD:238036	22/56 (39%)
		Hairy_orange	136..174	CDD:284859	14/46 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810