DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cwo and hes2.1

DIOPT Version :9

Sequence 1:	NP_524775.1	Gene:	cwo / 44669	FlyBaseID:	FBgn0259938	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	XP_021333940.1	Gene:	hes2.1 / 559147	ZFINID:	ZDB-GENE-081104-104	Length:	195	Species:	Danio rerio

Alignment Length:	139	Identity:	38/139 - (27%)
Similarity:	64/139 - (46%)	Gaps:	13/139 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 IIEKRRRDRMNSCLADLSRLIPPQYQRKGR--GRIEKTEIIEMAIRHLKHLQSECQQKESD-YRS 130
            ::|||||.|:|..|..|..||.|...:...  .::||.:|:||.:|.|:.|.|...:.::| |:.
Zfish    36 LMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTVRFLRDLPSSSAKGQTDSYKE 100

  Fly   131 GYMDCMKEAAKFLYDVHMQDFCHRLLGRLQEHIDEMFKTDCYKSTRSCHMPDNVSASSGSPHQAY 195
            ||..|::..:..|...:::...|       :.:.|..:.....|:.||   .|..|.:.......
Zfish   101 GYKACLQRISTMLPQSNLETEAH-------QRVSEFIQQSMASSSSSC---QNCCAQNSKMISQM 155

  Fly   196 HPPLCHLRD 204
            |..|..||:
Zfish   156 HQRLVSLRN 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cwo	NP_524775.1	HLH	66..118	CDD:306515	19/50 (38%)
cwo	NP_524775.1	ORANGE	126..168	CDD:128787	8/42 (19%)
hes2.1	XP_021333940.1	HLH	30..86	CDD:306515	19/49 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840