Protein Alignment cwo and HELT

DIOPT Version :9

• Sequence 1: NP_524775.1
• Gene: cwo / 44669
• FlyBaseID: FBgn0259938
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001287710.1
• Gene: HELT / 391723
• HGNCID: 33783
• Length: 242
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 80/349 - (22%)
• Similarity: 123/349 - (35%)
• Gaps: 126/349 - (36%)

  Fly    58 KTSRQDPLSHRIIEKRRRDRMNSCLADLSRLIPPQYQRKGRGRIEKTEIIEMAIRHLKHLQS--- 119
            |..::.|:||::||||||||:|.||.:|.:.:|....::..|::||.||:||.:::|:.|.|
Human     6 KERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADF 70

  Fly   120 -------ECQQKESDY-RSGYMDCMKEAAKFLYDVHMQDFCHRLLGRLQEHIDEMFKTDCYKSTR 176
                   |...:.::| ..||.:|||....:|..|                  |..:|   |.|:
Human    71 PRGREKAELLAEFANYFHYGYHECMKNLVHYLTTV------------------ERMET---KDTK 114

  Fly   177 SCHMPDNVSASSGSPHQAYHPPLCHLRDMLATSASDVEHSQDHNDVKDLSFRNHLNQLQRSQQAA 241
            ...:...:.:.:....:...|||..|.:                  .|.|::.|          .
Human   115 YARILAFLQSKARLGAEPAFPPLGSLPE------------------PDFSYQLH----------P 151

  Fly   242 AAAAVAAAAVAVANGSSPASNAGVDSKVPLTNGGGTGGAPPAADNVPSNSTGSGSAAACAGGNSN 306
            |....|        |.||    |..:..|..:|.|....||
Human   152 AGPEFA--------GHSP----GEAAVFPQGSGAGPFPWPP------------------------ 180

  Fly   307 SSGSNSSNAASSTICPPAGGSCPAKVTPLAAHQQPHQAPVITSTAPHHHHHHTDSSHHDFESSRE 371
                   .||.|    ||....|:...|||:..|.| :|.:|.......|:.....|
Human   181 -------GAARS----PALPYLPSAPVPLASPAQQH-SPFLTPVQGLDRHYLNLIGH-------- 225

  Fly   372 PILHTDTSNMHSPPPRDLLLQQHP 395
              .|.:..|:|:|        |||
Human   226 --AHPNALNLHTP--------QHP 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cwo	NP_524775.1	HLH	66..118	CDD:306515	23/51 (45%)
		ORANGE	126..168	CDD:128787	9/42 (21%)
HELT	NP_001287710.1	bHLH-O_HELT	14..69	CDD:381414	25/54 (46%)
		Hairy_orange	87..127	CDD:400076	11/60 (18%)
		PRK14951	<133..>207	CDD:237865	29/149 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140964
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1054305at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850