Protein Alignment cwo and HES5

DIOPT Version :9

• Sequence 1: NP_524775.1
• Gene: cwo / 44669
• FlyBaseID: FBgn0259938
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_005244808.1
• Gene: HES5 / 388585
• HGNCID: 19764
• Length: 198
• Species: Homo sapiens
• Alignment Length: 172
• Identity: 42/172 - (24%)
• Similarity: 65/172 - (37%)
• Gaps: 38/172 - (22%)

  Fly    69 IIEKRRRDRMNSCLADLSRLIPPQYQR-KGRGRIEKTEIIEMAIRHLKHLQSE------------ 120
            ::||.||||:||.:..|..|:..::.| :...::||.:|:|||:.:|||.:.|
Human    23 VVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSKGERARAPRAPSSHR 87

  Fly   121 -------------------------CQQKESDYRSGYMDCMKEAAKFLYDVHMQDFCHRLLGRLQ 160
                                     .:....||..||..|::||.:||......|...:||...|
Human    88 APAPPRPAARSPPPRLPAAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ 152

  Fly   161 EHIDEMFKTDCYKSTRSCHMPDNVSASSGSPHQAYHPPLCHL 202
            ....................|..:||.:.:...|.|.|.|.|
Human   153 RPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGL 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cwo	NP_524775.1	HLH	66..118	CDD:306515	20/49 (41%)
		ORANGE	126..168	CDD:128787	13/41 (32%)
HES5	XP_005244808.1	HLH	14..71	CDD:238036	18/47 (38%)
		Hairy_orange	118..153	CDD:295407	12/34 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140979
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840