Sequence 1: | NP_524775.1 | Gene: | cwo / 44669 | FlyBaseID: | FBgn0259938 | Length: | 698 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_035628.1 | Gene: | Bhlhe40 / 20893 | MGIID: | 1097714 | Length: | 411 | Species: | Mus musculus |
Alignment Length: | 427 | Identity: | 96/427 - (22%) |
---|---|---|---|
Similarity: | 142/427 - (33%) | Gaps: | 147/427 - (34%) |
- Green bases have known domain annotations that are detailed below.
Fly 55 RRNKTSRQD-PLSHRIIEKRRRDRMNSCLADLSRLIPPQYQRKGRGRIEKTEIIEMAIRHLK--- 115
Fly 116 HLQSECQQKESDYRSGYMDCMKEAAKFLYDVHMQDFCHRLLGRLQEHIDEMFKTDCYKSTRSCHM 180
Fly 181 PDNVSASSGSPHQAYHPPLCHLRDMLATSASDV-EHSQDHNDVKDLSFRNHLNQLQR-----SQQ 239
Fly 240 AAAAAAVAAAAVAV---------ANGS-SPASNAGVDSKVPL------TNGGGTGGAPPAADNVP 288
Fly 289 SNSTGSGSAAACAGGNSNSS--------------GSNSSNAASSTICPPA--------------G 325
Fly 326 GSCPAKVTPLAAHQQPHQAPVI--------TSTAPHHHHHHTDSSHHDFESSREPILH------- 375
Fly 376 TDTSNMHSPP--PRDLLLQQH--PHLAHSHHTQDSLM 408 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
cwo | NP_524775.1 | HLH | 66..118 | CDD:306515 | 21/54 (39%) |
ORANGE | 126..168 | CDD:128787 | 8/41 (20%) | ||
Bhlhe40 | NP_035628.1 | Essential for interaction with ARNTL/BMAL1, E-box binding and repressor activity against the CLOCK-ARNTL/BMAL1 heterodimer. /evidence=ECO:0000250 | 1..139 | 34/112 (30%) | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..20 | ||||
bHLH-O_DEC1 | 40..129 | CDD:381592 | 30/102 (29%) | ||
Necessary for interaction with RXRA and repressor activity against RXRA. /evidence=ECO:0000250 | 75..79 | 1/3 (33%) | |||
ORANGE | 140..184 | CDD:128787 | 14/78 (18%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 207..294 | 19/99 (19%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C167830933 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG4304 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.740 |