Protein Alignment cwo and Hey2

DIOPT Version :9

• Sequence 1: NP_524775.1
• Gene: cwo / 44669
• FlyBaseID: FBgn0259938
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_038932.1
• Gene: Hey2 / 15214
• MGIID: 1341884
• Length: 339
• Species: Mus musculus
• Alignment Length: 362
• Identity: 92/362 - (25%)
• Similarity: 152/362 - (41%)
• Gaps: 89/362 - (24%)

  Fly    25 SSFPYCTESSLNFSTSATAYSEDDAEYATGRRNKTSRQDPLSHRIIEKRRRDRMNSCLADLSRLI 89
            :::|....||:..|.|.|..|:     ...|:.:..        |||||||||:|:.|::|.||:
Mouse    24 NNYPGHATSSVMRSNSPTTTSQ-----IMARKKRRG--------IIEKRRRDRINNSLSELRRLV 75

  Fly    90 PPQYQRKGRGRIEKTEIIEMAIRHLKHLQS-------ECQQKESDYRS-GYMDCMKEAAKFLYDV 146
            |..::::|..::||.||::|.:.|||.||:       :.....:|:.| |:.:|:.|.|::|..|
Mouse    76 PTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGYFDAHALATDFMSIGFRECLTEVARYLSSV 140

  Fly   147 HMQDFCHRLLGRLQEHIDEMFKTDCYKSTRSCHMPDNVSASSGSPHQAYHPPLCHLRDMLATSAS 211
            ...|....|..||..|:          ||.:......|..||.:.|   |.|| |.....|..
Mouse   141 EGLDPSDPLRVRLVSHL----------STCASQREAAVMTSSMAHH---HHPL-HPHHWAAAF-- 189

  Fly   212 DVEHSQDHNDVKDLSFRNHL-------NQLQRSQQAAAAAAVAAAAVAVANGSS--PASNAGVDS 267
                             :||       |.|..|:......: .::.|..|:||:  .|:.|..||
Mouse   190 -----------------HHLPTALLQPNGLHTSESTPCRLS-TSSEVPSAHGSALLTATFAHADS 236

  Fly   268 KVPLTNGGGTGG-APPAADNVPSNSTGSGSAAACAGGNSNS---------------SGSNSSNAA 316
            .:.:.:||.... .||.:.::.|.|....:|||.|...::|               :.:.::.||
Mouse   237 ALRMPSGGTVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPSNAAAAAAVAA 301

  Fly   317 SSTICPPAGGSCPAKVTPLAAHQQPHQAPVITSTAPH 353
            ::.|.||..         ::|...|.|....|:..|:
Mouse   302 ATAISPPLS---------VSAASSPQQTSTGTNNKPY 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cwo	NP_524775.1	HLH	66..118	CDD:306515	24/51 (47%)
		ORANGE	126..168	CDD:128787	13/42 (31%)
Hey2	NP_038932.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		8/32 (25%)
		Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000269|PubMed:11486045	47..116		27/76 (36%)
		HLH	49..105	CDD:238036	26/63 (41%)
		ORANGE	120..165	CDD:128787	15/54 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	310..339		5/29 (17%)
		YQPW motif	329..332		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830929
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840