Protein Alignment wech and wech

DIOPT Version :10

• Sequence 1: NP_524772.2
• Gene: wech / 44653
• FlyBaseID: FBgn0259745
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: XP_314006.5
• Gene: wech / 1274803
• VectorBaseID: AGAMI1_005942
• Length: 875
• Species: Anopheles gambiae
• Alignment Length: 922
• Identity: 406/922 - (44%)
• Similarity: 551/922 - (59%)
• Gaps: 138/922 - (14%)

  Fly     2 MELLSNNSVPQQMASSNAPSANNVAHSSTANG--SGGGSVSSNASNSSERL-LAGILESFPAWDL 63
            |.||||.:...|:.            ..||||  :|||.......||::.: .:.:..:.|.||
Mosquito     1 MALLSNGASSMQIT------------PQTANGGPNGGGPDGPGDFNSNDHIFFSSLFNALPCWD- 52

  Fly    64 NVGLLPNVGQSSP---PRA---------------DFFINNFLGGLDT------------------ 92
                .|:...|.|   |::               |...:|.||.:.|
Mosquito    53 ----APHKASSGPVMVPQSNNNTSLDRDSISITEDILFSNVLGAIGTGSSSSGSSGAIGMGNVGI 113

  Fly    93 ----HGDFS--------------IGPIGSGARSNPKMSP------ESSNN----SSIS--CGWCE 127
                ||...              .|.|||...|:.:::|      .|||.    ||:.  ||.|:
Mosquito   114 IGSSHGSSGGGHLAHAVTSANEIFGVIGSSCASHAQLTPGTSPQTNSSNGSHCPSSVGAICGRCD 178

  Fly   128 VSASIRCLECNEFMCNDCLREHRNSPLSSNHSIVSLPT--PIGASP-----TGGSSVNAQTPPSG 185
            ..||.|||:||:.:|.||.:.|..:..:.:|.::|:.|  |||::|     .|..|.|...|.:|
Mosquito   179 THASSRCLDCNDVLCEDCTQLHGKNAFTKDHCVISINTISPIGSAPCMVPGNGHGSGNGSGPSNG 243

  Fly   186 NFI-------CDIHNEMLRYVCDYCRKLVCQCCTLHEHKEHSYASIQSFMVGSKEKLEGAIESSQ 243
            ...       ||:|.|:|||:|:.|:|:|||.|||.:||:||...:.:...|:.||:...:||.:
Mosquito   244 PMAAGLSEPHCDVHGEVLRYLCESCKKVVCQECTLWDHKDHSCIPVANISHGASEKIMSILESGK 308

  Fly   244 VGTRCIKSSIDKALAFIRLIERNCSELSDNIRKAFRQFIIAIEDRERFLLDFVEKLRQRRLAILH 308
            :||:.||:|||:|:.:.:.:||:..|.|..||||.|.||:|.|||||.|||.|:|.||::|..|.
Mosquito   309 LGTKYIKASIDRAVTYSQAVERDAMEASARIRKAMRHFILAAEDRERTLLDRVDKFRQQKLTSLS 373

  Fly   309 DQMAGLKSALAGLSETSDMLSKVADNACNMDQIEIAMKLTNGQRQMEQFAGIYKDLQPKQEVFAF 373
            ||||||::||||||:|||||:|..|:...|..:|||..||.|:.||||||.:||:||||:|...|
Mosquito   374 DQMAGLRAALAGLSQTSDMLTKALDSVSVMGSMEIAKTLTTGESQMEQFAAMYKNLQPKEEFITF 438

  Fly   374 APPDYSLLQDIRNQGGVILVDDKNLPIVSSSNGIVPSVSSVNAVAAASVGV-VGGV--AGVVGGV 435
            ..|::.|||:||.||.|:||..::..:.|:|:|        ||......|. .|||  :..||||
Mosquito   439 VAPNFELLQEIRMQGDVMLVGQRSNSVSSNSSG--------NASLQGPTGPNCGGVNPSNGVGGV 495

  Fly   436 GVSNGLDLAFGMNMPNNPLSVASSSVRRPLLRDN--SFRIPSPIMQPRGGSACGMSSGMSSAALD 498
            ||..               ||.:...|||::|..  :.||.|...:|.|..:.|.||.:.|:...
Mosquito   496 GVVG---------------SVGNILTRRPIVRSTTPAQRIGSSSWEPMGKGSSGSSSVLGSSPTS 545

  Fly   499 WELNGLRSSPGLHFSAPRTTQAIPGCMDLVKVRNSNALSLSFATEGHEDGQVSRPWGLCVDKMGH 563
            :   |:...||    ||...|.||||.:.|..:.:...||:|..:||||||||||||:.|||.|.
Mosquito   546 F---GIGPIPG----APILGQCIPGCNNHVAAKPAVGPSLTFGFDGHEDGQVSRPWGITVDKDGQ 603

  Fly   564 VLVSDRRNNRVQVFNPDGSLKFKFGRKGVGNGEFDLPAGICVDVDNRIIVVDKDNHRVQIFTASG 628
            :||:||||||||:|.|||:.|.|||.||..||:||||||||.|...|||||||||||||:|:|.|
Mosquito   604 ILVADRRNNRVQIFYPDGTFKLKFGSKGTANGQFDLPAGICTDGQGRIIVVDKDNHRVQVFSAGG 668

  Fly   629 VFLLKFGSYGKEYGQFQYPWDVAVNSRRQIVVTDSRNHRIQQFDSEGRFIRQIVFD--NHGQ-TK 690
            :|||||||||||.||||||||||||::.:|:||||||||||.|..:|.||.:..||  ||.: .|
Mosquito   669 LFLLKFGSYGKECGQFQYPWDVAVNTKGEILVTDSRNHRIQLFSPDGLFISRYSFDGVNHSRYLK 733

  Fly   691 GIASPRGVCYTPTGNIIVSDFDNHCLYLIDPDINDILSVKGHEGSGFHEFNRPSGLCCDDEGRII 755
            |:.:|||.|:||.|:||:|||:||.|.|||..::.:|:.||||||..|||:||||:||||:||:|
Mosquito   734 GLTTPRGACFTPQGDIIISDFENHRLLLIDATLSKVLAAKGHEGSAVHEFSRPSGICCDDDGRVI 798

  Fly   756 VADSKNQRILVFNQNLDFMWDIEVRPSINPLMPPTLDEKDRTCDVAIMPDGRIVFLIELSPDSKE 820
            ||||||||:|||:..|:|:|.:|:|||.|.|:...:|||||..|||::||||:|.::|.|||:::
Mosquito   799 VADSKNQRVLVFSPQLEFLWAVEIRPSSNGLLAIGMDEKDRPSDVALLPDGRLVVMVETSPDARD 863

  Fly   821 GSNPYKRFVHVF 832
            ..:|.|.|:.::
Mosquito   864 QCSPQKTFIQIY 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wech	NP_524772.2	Bbox1	123..163	CDD:380815	15/39 (38%)
		Bbox2_TRIM66-like	187..228	CDD:380852	20/47 (43%)
		CC_brat-like	232..343	CDD:475168	58/110 (53%)
		NHL_TRIM71_like	528..810	CDD:271324	182/284 (64%)
		NHL repeat	553..592	CDD:271324	26/38 (68%)
		NHL repeat	600..639	CDD:271324	30/38 (79%)
		WD40 repeat	603..640	CDD:293791	28/36 (78%)
		WD40 repeat	647..684	CDD:293791	22/36 (61%)
		NHL repeat	647..683	CDD:271324	22/35 (63%)
		WD40 repeat	692..736	CDD:293791	24/43 (56%)
		NHL repeat	692..733	CDD:271324	21/40 (53%)
		NHL repeat	742..772	CDD:271324	22/29 (76%)
		WD40 repeat	743..767	CDD:293791	19/23 (83%)
wech	XP_314006.5	None