Protein Alignment wech and tn

DIOPT Version :10

• Sequence 1: NP_524772.2
• Gene: wech / 44653
• FlyBaseID: FBgn0259745
• Length: 832
• Species: Drosophila melanogaster
• Sequence 2: XP_308626.5
• Gene: tn / 1269971
• VectorBaseID: AGAMI1_013811
• Length: 1351
• Species: Anopheles gambiae
• Alignment Length: 884
• Identity: 208/884 - (23%)
• Similarity: 322/884 - (36%)
• Gaps: 235/884 - (26%)

  Fly     6 SNNSVPQQMASSNAPSANNVAHSSTANGSGGGSVSSNASNSSERLLAGILESFPAWDLNV---GL 67
            ||....:|.:..:.|:|.  |.::|...|...|.||.:::|||......:.:....|..|   .:
Mosquito   581 SNRRTARQTSVGSKPAAG--AAAATKKSSVTRSASSESNSSSESSSPSPVPASTRTDPEVKPKTI 643

  Fly    68 LPNVGQSSPPRADFFINNFLGGLDTHGDFSIGPIGS--------GARSNPKMSPESSNNSSISCG 124
            |.|..:::..|         .|..:..:.:..|..|        .|::.|:...||.::|.
Mosquito   644 LKNANENASQR---------NGTASPTETAKKPFQSRFLPQTQPPAQTAPEKKEESESSSE---- 695

  Fly   125 WCEVSASIRCLECNEFMCNDCLREHRNSPLSSNHSIVSLPTPIGA-------SP----TGGSSVN 178
              |.|:|....|..|       .|....|.::       |.|..|       ||    |..|...
Mosquito   696 --EESSSEEESEEEE-------EEEEEKPAAA-------PAPAAAANSTARSSPITTTTSSSRTT 744

  Fly   179 AQTPPSGNF-----------ICDIHNEMLRYVCDYCRKLVCQCCTLHEHKEHSYASIQSFMVGSK 232
            ..||.|..|           ......:.||....|...      |.:..:.| |...:|...||.
Mosquito   745 HDTPSSPLFGRVSRQDSSDSTRKSSRDELRTSSGYSSP------TSYRSQNH-YERDESPKYGSS 802

  Fly   233 EKLEGAIESSQVGTRCIKSSIDKALAFIRLIERNCSELSDN------------IRKAFRQFIIAI 285
            .....|:.|....                    :.:|..||            :.|:....::|.
Mosquito   803 SSGSSALRSRTTS--------------------HAAEPEDNKYGSGSGYTSRFLNKSKSTAVVAP 847

  Fly   286 ED--------------RERFLLDFVEKLRQRRLAILHDQMA------------------------ 312
            ||              |.||     ..|:.||..:...:.:
Mosquito   848 EDDATDDSDSRYGAGGRSRF-----TALQDRRTRLARSRSSHNFGNDDEEDEPVSPTTTSPSAYL 907

  Fly   313 ----GLKSALAGLSETSDMLSKVADNACNMDQIEIAMKLTNGQRQMEQFAGIYKDLQPKQE---V 370
                |..|:||  |:.||:....:.:|                         .|..:|..|   .
Mosquito   908 ASRYGASSSLA--SQPSDLSRSRSTHA-------------------------LKSREPSPERNST 945

  Fly   371 FAFAPPDYSLLQD----IRNQ-GGVILVDDKNLPIVSSSNGIVPSVSSVNAVAAASVGVVGGVAG 430
            .|....|.:.|..    ::|: |.....|.|:.|..|||...:.|.|..:..:|:|.....|.:.
Mosquito   946 GAGGDKDGAALSSWARYLKNKYGNRTTKDGKDSPSSSSSTSGLGSSSLSSPSSASSSSATSGSSA 1010

  Fly   431 VVGGVG--VSNGL------------DLAFGMNMPNNPLSVASSSVRRPLLRDNSFRIPSPIMQPR 481
            ......  :|.||            |...|:..|.:|.:.|::....|
Mosquito  1011 SASAAARRLSLGLPLRQTDLLSSDDDSKNGVGSPTSPTAAAAAVAGIP----------------- 1058

  Fly   482 GGSACGMS---SGMSSAALDWELNGLRSSPGLHFSAPRTTQAIP--------GCMDLVKVRNSNA 535
              .|.|||   ..:......:::.|..|.|| .|:.||.....|        .....|:|.:||.
Mosquito  1059 --GAAGMSPRTQYLQKRRQLFQIGGRGSEPG-SFTWPRGIAVGPDNSIVVADSSNHRVQVFDSNG 1120

  Fly   536 LSL-SFATEGHEDGQVSRPWGLCVDKMGHVLVSDRRNNRVQVFNPDGSLKFKFGRKGVGNGEFDL 599
            :.: .|...|:.||:.....|:.|:::|..:::||.|:|:||.:|.|.....||.:|..:|:|:.
Mosquito  1121 IFVKEFGQYGNGDGEFDCLAGVAVNRIGQFIIADRYNHRIQVLDPAGRFLRSFGSQGTTDGKFNY 1185

  Fly   600 PAGICVDVDNRIIVVDKDNHRVQIFTASGVFLLKFGSYGKEYGQFQYPWDVAVNSRRQIVVTDSR 664
            |.||..|....|.|.||:|||:|:|.:.|.|:.|||:.|||.||.::|..:||::..:::|:||.
Mosquito  1186 PWGITTDALGFIYVCDKENHRIQVFQSDGSFIGKFGTCGKEKGQLEHPHYIAVSNTNRVIVSDSN 1250

  Fly   665 NHRIQQFDSEGRFIRQIVFDNHGQTKG-IASPRGVCYTPTGNIIVSDFDNHCLYLIDPDINDILS 728
            |||:|.||..||.:  ..|...|..:| ...||||.....|.|.|:|..|:.:.:..|| ...|.
Mosquito  1251 NHRVQIFDVNGRVL--TTFGGEGSEEGQFKFPRGVAVDDQGYICVADSGNNRIQIFHPD-GSFLR 1312

  Fly   729 VKGHEGSGFHEFNRPSGLCCDDEGRIIVADSKNQRILVF 767
            ..|..|||..||....|:.....|.|:|.|.:|.|:.||
Mosquito  1313 AFGSWGSGDAEFKGLEGVAIMSNGNILVCDRENHRVQVF 1351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wech	NP_524772.2	Bbox1	123..163	CDD:380815	7/39 (18%)
		Bbox2_TRIM66-like	187..228	CDD:380852	8/51 (16%)
		CC_brat-like	232..343	CDD:475168	23/164 (14%)
		NHL_TRIM71_like	528..810	CDD:271324	91/242 (38%)
		NHL repeat	553..592	CDD:271324	13/38 (34%)
		NHL repeat	600..639	CDD:271324	18/38 (47%)
		WD40 repeat	603..640	CDD:293791	17/36 (47%)
		WD40 repeat	647..684	CDD:293791	14/36 (39%)
		NHL repeat	647..683	CDD:271324	14/35 (40%)
		WD40 repeat	692..736	CDD:293791	14/43 (33%)
		NHL repeat	692..733	CDD:271324	13/40 (33%)
		NHL repeat	742..772	CDD:271324	9/26 (35%)
		WD40 repeat	743..767	CDD:293791	7/23 (30%)
tn	XP_308626.5	None