Protein Alignment Cnx99A and Cnx99A

DIOPT Version :10

• Sequence 1: NP_477157.1
• Gene: Cnx99A / 44643
• FlyBaseID: FBgn0015622
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_001688470.2
• Gene: Cnx99A / 1274867
• VectorBaseID: AGAMI1_007065
• Length: 635
• Species: Anopheles gambiae
• Alignment Length: 660
• Identity: 343/660 - (51%)
• Similarity: 435/660 - (65%)
• Gaps: 91/660 - (13%)

  Fly     1 MAWKMGGNRAATLALLFASSLLLLSAANAAD-LDTESDDFEDGYVEDVQEEPAVIGGDEKLAYES 64
            :.|:        :|||.|..|......:..| :.|||             :||   ||.: .||:
Mosquito    12 LLWR--------IALLSAVLLFHNPVVHGNDEISTES-------------QPA---GDAE-QYET 51

  Fly    65 PVIDAKKFHFADHFDDV-----EESRKRWVLSQAKKDDIAEEISKYDGIWNWESPQRIVWANDLG 124
            |.:|.|:.:||:||||:     :...||||.|:|||||.|||::||||.|..|.|||.:.|||.|
Mosquito    52 PTVDPKRMYFAEHFDDLFDGASDAIEKRWVKSKAKKDDAAEEVAKYDGEWAVEQPQRPILANDYG 116

  Fly   125 LVLKSKAKHAAIAAP--LRKPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFN 187
            |||||||||||||:|  |.:||.|: ||||||||||.|||||||||||:||||.|..|:.||.|:
Mosquito   117 LVLKSKAKHAAIASPLLLNRPFVFE-DKPLVVQYEVNLQEGQECGGSYIKLLSVGDGTKDLKQFH 180

  Fly   188 DKTPYTIMFGPDKCGNDVKMHFIFRHVNPINGTITEKHCNKPKNRLEEPFKDKLPHLYQLVVRPD 252
            |||||||||||||||||||:|||||||||||||||||||||.|:||::|||||.||||||::|||
Mosquito   181 DKTPYTIMFGPDKCGNDVKLHFIFRHVNPINGTITEKHCNKQKDRLDDPFKDKRPHLYQLIIRPD 245

  Fly   253 NSFEIRVDHKIINEGSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPP 317
            |::.||||||.:|||||||:|.|.||||||||||.|.|||:||:|||||||.|.||:||:||.|.
Mosquito   246 NTYTIRVDHKTVNEGSLLTNFTPAVNPPAEIDDPEDRKPENWDDREKIPDPEATKPDDWNEDEPA 310

  Fly   318 QLPDTDAVMPNGWLEDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIP 382
            |:||..|..|.|||:|..:|:.|.:|.||||||.::|||||.||:.||:||||.|||.||||::|
Mosquito   311 QIPDPKATKPAGWLDDVEEMVPDSSAVKPEDWDNDMDGEWEPPLIPNPMCEKAVGCGLWKAPMVP 375

  Fly   383 NPNYKGKWRAPMIENPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLII 447
            |||||||||||:|.|.||||||||||||||||||||.||:||||:|||:||||||:||||||::|
Mosquito   376 NPNYKGKWRAPLIANVNYQGKWAPRKIPNPDFFEDLTPFRMTPIAAVGIELWSMSNDILFDNIVI 440

  Fly   448 TDDVEVARDFAANSFDIKRRYIDRESDSFVNKVVELAKANPSIWGIGLVAIVALVALTIYCR--- 509
            .||..||.::||.:||:|.:.:||::.:..::.:......|..||          |..:||.
Mosquito   441 CDDESVADEWAAQTFDLKVKTLDRQAQTLWDRAMRYINYKPGYWG----------AYFVYCSIPL 495

  Fly   510 ------FGTAKSQDSAAKKAAAEAKKSDD-PQPDDEPE------AEEESDERAAGDTSKESTPLS 561
                  ..:.:.::..||......||:|| |.|:.|.:      .||..|:..:..|...:....
Mosquito   496 IAYVWFLWSRRDKEGDAKAEIGRKKKNDDYPAPEQEQDELVGGAGEEAEDDGRSSKTKLNAAATG 560

  Fly   562 ASPKKNQKS------------DLDDNEEESKAAESREPAQTEESNTK------------------ 596
            :|..::..|            |.|:.||:.:..|::|.||..|:..:
Mosquito   561 SSGSRSASSAGEAYAENEDERDGDEAEEDEEDDEAQEEAQEMEAGEEEASSSDAPVDSKNSEGGE 625

  Fly   597 -TRKRQARKE 605
             .:||:|||:
Mosquito   626 GLKKRRARKD 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnx99A	NP_477157.1	Calreticulin	74..447	CDD:459737	277/379 (73%)
Cnx99A	XP_001688470.2	None