Protein Alignment Cnx99A and LOC1274052

DIOPT Version :10

• Sequence 1: NP_477157.1
• Gene: Cnx99A / 44643
• FlyBaseID: FBgn0015622
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_313116.1
• Gene: LOC1274052 / 1274052
• VectorBaseID: AGAMI1_015122
• Length: 406
• Species: Anopheles gambiae
• Alignment Length: 568
• Identity: 167/568 - (29%)
• Similarity: 244/568 - (42%)
• Gaps: 175/568 - (30%)

  Fly    12 TLALLFASSLLLLSAANAADLDTESDDFEDGYVEDVQEEPAVIGGDEKLAYESPVIDAKKFHFAD 76
            |||:|||:.|    |.||...      ||:|:.:|..::..|....:.:.|...|..|.||
Mosquito     3 TLAVLFAAFL----AVNAKVY------FEEGFKDDSWQKTWVQSEHKGVEYGKFVHTAGKF---- 53

  Fly    77 HFDDVEESRKRWVLSQAKKDDIAEEISKYDGIWNWESPQRIVWANDLGLVLKSKAKHAAIAAPLR 141
             ::|.|.                                      |.||.....|:..|::...
Mosquito    54 -YNDAEA--------------------------------------DKGLQTSQDARFYALSNKF- 78

  Fly   142 KPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFNDKTPYTIMFGPDKCG-NDV 205
            .||..|.| .||:|:.|..::..:|||.|||:.....|.:.|   :.:|||.:|||||.|| ...
Mosquito    79 TPFSNKDD-TLVIQFSVKHEQNIDCGGGYLKVFDCSVDQKDL---HGETPYLVMFGPDICGPGTK 139

  Fly   206 KMHFIFRHVNPINGTITEKHCNKPKNRL-EEPFK---DKLPHLYQLVVRPDNSFEIRVDHKIINE 266
            |:|.||.:              |.||.| .:..:   |...|.|.||||.||::|:.:|::.:..
Mosquito   140 KVHVIFSY--------------KGKNHLINKDIRCKDDVFTHFYTLVVRADNTYEVLIDNEKVES 190

  Fly   267 GSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPPQLPDTDAVMPNGWL 331
            |||..|:  ...||.:|.||...|||.||:|..|.||...|||||
Mosquito   191 GSLEDDW--DFLPPKKIKDPEAKKPEDWDDRATIADPDDTKPEDW-------------------- 233

  Fly   332 EDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIPNPNYKGKWRAPMIE 396
             |:|:.|.||.||||:|||.|:|||||.|::|                   ||.|||:|:...|:
Mosquito   234 -DKPEHIPDPDATKPDDWDDEMDGEWEPPMID-------------------NPEYKGEWKPKQID 278

  Fly   397 NPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAANS 461
            ||.|:|.|...:|.||::.||...:....:.|||:::|.:.|..:|||.:||:|:|.|:..||:.
Mosquito   279 NPAYKGVWVHPEIDNPEYEEDKSLYLREEVCAVGIDVWQVKSGTIFDNFMITNDLEEAKKVAASV 343

  Fly   462 FDIKRRYIDRESDSFVNKVVELAKANPSIWGIGLVAIVALVALTIYCRFGTAKSQDSAAKKAAAE 526
                     :|:.....||.:..:                           |:.:..|.::||||
Mosquito   344 ---------KETQEGEKKVKDAQE---------------------------AEERKKAEEEAAAE 372

  Fly   527 AKKSDDPQPDDEPEAEEESDERAAGDTSKESTPLSASPKKNQKSDLDD 574
            ....||...|||.:|:                  :|.|  .:.::|||
Mosquito   373 EAAKDDEDEDDEDDAD------------------NALP--GEATELDD 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnx99A	NP_477157.1	Calreticulin	74..447	CDD:459737	120/377 (32%)
LOC1274052	XP_313116.1	Calreticulin	20..329	CDD:459737	130/412 (32%)