DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cutlet and CTF18

DIOPT Version :9

Sequence 1:	NP_787969.1	Gene:	cutlet / 44637	FlyBaseID:	FBgn0015376	Length:	993	Species:	Drosophila melanogaster
Sequence 2:	NP_171966.2	Gene:	CTF18 / 839431	AraportID:	AT1G04730	Length:	943	Species:	Arabidopsis thaliana

Alignment Length:	1012	Identity:	280/1012 - (27%)
Similarity:	435/1012 - (42%)	Gaps:	212/1012 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 MPAIQELENTQLTSRSYGLEKENAAAN----------------QLQEVGLKNVNKRRLE------ 162
            :|..:|||..:..|..|  |:|:...|                :.:.|..|..:.|:.|
plant     5 IPLPEELELLEANSHFY--EEEDEYLNFEEPPYPYPIDGDEEKEEERVAHKEPHVRQSESSDIKG 67

  Fly   163 ----RDLFGD----IDDLFHESYEDPMVKKARTE-EQRDHEAIERILELRRKMRESSKTL--RKD 216
                |.|..|    :|::...|.:...:...|.| |..|......:.|:...|.|..:.:  ::.
plant    68 CKRPRSLISDPIVNLDEVSPASDKRSKIDDNRVEIEDEDWLRFSPVKEVVHVMEEEEEVVIPQET 132

  Fly   217 DVSRLKALHDFKMRNLSYEIPNWPFLAIQRSDLERIYVRFHSE--DYEQRQLDLISARGEVVGSL 279
            .:||..:..|.:.         :|..|....|  |:|.:|...  |.|..:||:......::...
plant   133 MLSRYASEIDGEC---------FPITAPDGGD--RVYAKFCRALGDEEVNKLDVKDKSNGLIKDP 186

  Fly   280 LGEAKDKIWQEAGEIVLSRATAAEDADVTLVNSNANSEPGRLWVDKYKPRKYIDLLSDEMTNRSL 344
            :.....:..:||...||.  .::||.:.| :::..:....:||||||.|..:.:|||||.|||.:
plant   187 ISVLLQQSEKEAFNKVLQ--ASSEDQNET-ISAETSVMHEKLWVDKYSPSSFTELLSDEQTNREV 248

  Fly   345 LYWLKMWDKVVFGKAFHSKRE-------QEAVTGEGGTAGGAANQLNSFNKRTGKFESNGGWRQR 402
            |.|||.||..|||....|..|       :.:.|.....:..|..:...|| |..| ||.|   ..
plant   249 LLWLKQWDASVFGSEIRSTTEAVLSALKRHSTTSHHQKSDSAFTRKKQFN-RWSK-ESFG---YS 308

  Fly   403 KSRQALNTNVDAL-----------GRPMQKVALLCGPPGLGKTTLAHTIARHAGYNVREINASDD 456
            |:.:..|||...:           |.|.||:.||||.||||||||||..|:|.||.|.||||||:
plant   309 KNAEVSNTNTADINDLWNKKSKLTGPPEQKILLLCGAPGLGKTTLAHIAAKHCGYRVVEINASDE 373

  Fly   457 RSPEAFKLALENGTQMSSVLNEDKRPNCIVLDEIDGA---PRQSIDYLVKFISDAVYTKVKAKGA 518
            ||..|.:..:.:..||:|| ..|.||.|:|:||||||   .:.::|.::|.:   :..:..|.|.
plant   374 RSASAIETRILDVVQMNSV-TADSRPKCLVIDEIDGALGDGKGAVDVILKMV---LAERKHATGK 434

  Fly   519 KAEHNV------------LKRPIICICNDVYDPALRPLRQVAFVVTFPPIDAARLAERLVKIAFK 571
            :...||            |.||:||||||:|.||||||||:|.|..|.....:|:..||..|...
plant   435 ENVENVKTSSKKDRRTAPLSRPVICICNDLYAPALRPLRQIAKVHIFVQPTVSRVVNRLKYICNM 499

  Fly   572 EQLKTDFGSLIALAEKSGNDVRSCISSMQFFNAQKHSLTLQDVLNNNLGQKDRHQGLFAVWDAIF 636
            |.:|....:|.||||.:..|:|||::::||...:|.::.:.|:.:..:|:||..:.||.:|..||
plant   500 EGMKARSFALSALAEYTECDIRSCLNTLQFLYKKKETINVIDIGSQVVGRKDMSKSLFDIWKEIF 564

  Fly   637 RIQRPRKTLHTDANKVDEPAQVTMTNTSVTTRVRN---VLEVVHSSGDYERLTQGVYENYLQQKM 698
            ..::.::....||:               .:..:|   :..:|.|.|||:.:..|::||.||...
plant   565 TTRKMKRERSNDAS---------------GSGAKNFDFLHSLVSSRGDYDLIFDGIHENILQLHY 614

  Fly   699 PDPNFTGVCEALKWFCFTDTVQHQISRQQNYSVYPYLQYGFVAWHLLFATLAWPKIAFPTRGFEF 763
            .||........|.....:|.:...|.|.|...:|.|.....:..|...|.:..|.|.:|
plant   615 HDPVMDKTISCLDGLGTSDLLHRYIMRTQQMPLYVYFPSLVIPIHRRVAQIQKPMIEWP------ 673

  Fly   764 QQKSTNQRNIFQALCKGVTTSALGVGQGGTLLL----------------------------DTV- 799
              ||.::       |:             |||:                            |::
plant   674 --KSYHR-------CR-------------TLLVEKQESLRSWHHKIPPYIGRHLSIKSFVEDSIS 716

  Fly   800 PLLKRILSPQLRSVAVQLLSPKEQQDLRHTIEVMVDLGLTFVQVKSQ-----------EGHYVFQ 853
            |||..:..|.||.||..|||.::::.|...:.:|....||:..|||.           ....|..
plant   717 PLLHILSPPTLRPVASHLLSDRQKEQLAGLVMLMCSYSLTYKNVKSDPVLSSLREDAASDALVLA 781

  Fly   854 TEPDLDALSAFPGY------TGLSLPYFSRQLIAREVDLERIRRAA-PKGGAPSAPAAK------ 905
            .:|.|.....|.|:      ..|::    :|::..||:.::|.:|: .|.|..:.|..|
plant   782 LDPHLFDFINFKGHQFKHHVLALAM----KQVLVHEVEKQKILQASGGKSGILNKPEIKKINQDL 842

  Fly   906 -KKTSGAAAQLPNHLQTLKPKPIS----------ASNMHSAPKQQLTKDFFGRITHKSTSTNSAE 959
             |||:.||.:......|.||..:|          :|::..|.:..|  :||.|...........|
plant   843 AKKTNAAANESQRTPVTSKPPSVSVGTATTSKPNSSDVKKASRNAL--NFFDRFRKSRKDYEDPE 905

  Fly   960 ESKTDAIVK---SPIWYRYKEGFNNAVRKDVHIHELL 993
            :.:..|..|   .|:.:::.|||.|||::.|.:.|.|
plant   906 DVQNRATAKRDSRPLLFKFNEGFTNAVKRPVRMREFL 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cutlet	NP_787969.1	AAA	424..555	CDD:99707	70/145 (48%)
CTF18	NP_171966.2	PRK04195	337..>650	CDD:235250	120/331 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	141	1.000	Domainoid score	I1524
eggNOG	1	0.900	-	-		E1_KOG1969
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32532
Inparanoid	1	1.050	297	1.000	Inparanoid score	I800
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D307415at2759
OrthoFinder	1	1.000	-	-		FOG0005061
OrthoInspector	1	1.000	-	-		oto2962
orthoMCL	1	0.900	-	-		OOG6_102931
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3581
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.730