Protein Alignment cutlet and ctf18

DIOPT Version :10

• Sequence 1: NP_787969.1
• Gene: cutlet / 44637
• FlyBaseID: FBgn0015376
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: NP_595200.1
• Gene: ctf18 / 2541270
• PomBaseID: SPBC902.02C
• Length: 960
• Species: Schizosaccharomyces pombe
• Alignment Length: 1089
• Identity: 272/1089 - (24%)
• Similarity: 434/1089 - (39%)
• Gaps: 227/1089 - (20%)

  Fly     1 MDQYPDENEEFELQYQDELELL-------------EDLPDEFNAYDGPSTSKQAAEKQKENRAPV 52
            ||..|:|         |:||.|             |...||.| |.....:..|.|..:....|.
pombe     1 MDSIPNE---------DDLEKLLVAEQNVPYGKNYESFEDEEN-YLLELRNANALENLEHRSIPN 55

  Fly    53 AALRDSTRLGNSTLGSPQL-SQITFGASQLG------GEEEAEGTSSGGQVNRRLFGTPKGPPVG 110
            .....|..:|:.|.....: |.:...:|...      .|:|........|.:.|...|...|.:|
pombe    56 DLFHSSQPVGSPTRNGDDIPSTLDLYSSDNAAIDTDISEDETINQRHAPQTDYRYPNTSANPKMG 120

  Fly   111 RGCSTPFQRMPAIQ-ELEN-------TQLTSRSY-------------GLEKENAAANQLQEVGLK 154
            ...|.... ||:|. ::.|       :.|..|:|             ..||||..:|.|...|..
pombe   121 LEESMDID-MPSIDLDISNAAAFPRDSNLLFRNYNSHTKTSEKGSPVNFEKENQDSNVLFSTGRT 184

  Fly   155 NVNKRRLERD--------LFGDIDDLFHESYEDPMVKKARTEEQRDHEAIERILELRRKMRESSK 211
            :|.....|:.        |..|...||  |:|:. |..|..:...|    :::...:...|.|..
pombe   185 SVLHIDAEQSQTNNTVTPLKDDALSLF--SFEND-VNGAVNDNSLD----QKLSASKNSQRVSLP 242

  Fly   212 TLRKDDVSRLKALHDFKMRNLSYEIPNWPFLAIQRSDLERIYV----RFHSED---YEQRQLDLI 269
            ...|.::....:.             :.|.::.:.|..:.||.    ..||:.   ..:|..|.|
pombe   243 FFSKIELDEGSSF-------------SGPKISARTSSGKIIYFPKKKNRHSDGLLLQPKRLADEI 294

  Fly   270 SARGEVVGSLLGEAKD---------KIWQEAGEIVLSRATAA---EDAD-VTLVNSNANSEPGRL 321
            |...|:       .||         :||.|...||....:.|   |..| :.:.|.....:..:|
pombe   295 SQVNEI-------GKDFNQDLLNSVRIWSENFLIVSKEKSVALKTEKLDSLQITNCTTKPQSQKL 352

  Fly   322 WVDKYKPRKYIDLLSDEMTNRSLLYWLKMWDKVVFGKAFHSKREQEAVTGEGGTAGGAANQLNSF 386
            |||.|:|:.:.|||.||..:|:.::|:|.||..||||:    |.|             .::...|
pombe   353 WVDTYRPQLFRDLLGDERVHRAAMHWIKAWDPCVFGKS----RLQ-------------PSKSMRF 400

  Fly   387 NKRTGKFESNGGWRQRKSRQALNTNVDALGRPMQKVALLCGPPGLGKTTLAHTIARHAGYNVREI 451
            |.|.....|:.                  .||.:::.:|.|..|.|||||||.||..|||.|.||
pombe   401 NPRFTNITSDS------------------DRPDKRIMMLTGLAGAGKTTLAHVIAHQAGYKVLEI 447

  Fly   452 NASDDRSP----EAFKLALENGTQMSSVLNEDKRPNCIVLDEIDGAPRQSIDYLVKFI-SDAVYT 511
            ||||||:.    |....|:.|.:.:||      :|.|:::|||||.....:..|:..: ||...|
pombe   448 NASDDRTAHTVHEKVSSAISNHSALSS------QPTCVIVDEIDGGDPAFVRALLSLLESDEKAT 506

  Fly   512 KVKAKG---AKAEHNVLKRPIICICNDVYDPALRPLRQVAFVVTFPPIDAARLAERLVKIAFKEQ 573
            :....|   .|.:...|.|||||||||:|.|||||||..|.::.|.|...|.|..||..|...|.
pombe   507 EYSQAGNSKKKKKFKKLCRPIICICNDLYTPALRPLRPYAQIIYFRPPPQASLVGRLRTICRNEN 571

  Fly   574 LKTDFGSLIALAEKSGNDVRSCISSMQFFN-----AQKHSLTLQDVLNNNLGQKDRHQGLFAVWD 633
            :..|..||..|.:...:|:||||:|:|..:     ....::.|....:|:.......|.||
pombe   572 IAVDSRSLTLLTDIYNSDIRSCINSLQLLSLNNKRIDSETIKLLQPKSNSFSTSSLIQSLF---- 632

  Fly   634 AIFRIQRPRKTLHTDANKVDEPAQVTMTNTSVTTRVRNVLEVVHSSGDYERLTQGVYENYLQQKM 698
                :|...|.:     :..|.:|.|.::...      :|..:..:.|.|.:....:..||....
pombe   633 ----LQLDNKQI-----RAIEASQPTYSHLDA------LLARIDGANDSESVLMNCFHTYLDLPF 682

  Fly   699 PDPNFTGVCEALKWFCFTDTVQHQISRQQNYSVYPYLQYGFVAWHLLFATLAWPKIAFPTRG-FE 762
            .|...:......:|..|.|.: |....:.||.::.|:.|..:.:|.|:||....::..|.|. .|
pombe   683 TDSLLSKPALTSEWLYFFDQL-HSQCYKGNYELWRYIPYSIIHFHYLYATPEKCRLPHPPRSDLE 746

  Fly   763 FQQKSTNQRNIFQALCKGVTTSALGVGQGGTLLLDTVPLLKRILSPQLRSVAVQLLSPKEQQDLR 827
            ..:....::.|..:....:......:....::||:.:..:...::|.|:.....:........:.
pombe   747 ALKLYRTRKEILDSFISTLNAYENQMHGERSILLELIRTILITINPTLKQKEDSMPRSALPSKIE 811

  Fly   828 HTIEVMVDLGLTFVQVKSQEGHYVFQTEPDLDALSAFPGYTGLSLPYFSRQLIAREVDLERIRRA 892
            |.|.::....|.|.|:...:|:||::.||.||.|.    :...:..|..||::::|:..:|:
pombe   812 HAINILNHYNLRFQQLPVGDGNYVYRLEPPLDELV----WDAPTSSYSVRQMLSQELLKKRL--- 869

  Fly   893 APKGGAPSAPAAKKKTSGAAAQLPNHLQTLKPKPISASNMHSAPKQQ-------LTKDFFGRI-- 948
                      |..||            |||...|.|:   :|:.|::       :.:||||||
pombe   870 ----------ADIKK------------QTLTDNPTSS---NSSRKRKDFNSGKAIKRDFFGRIIS 909

  Fly   949 ---THKSTSTNSAEESKTDAI-VKSPIWYRYKEGFNNAVRKDVHIHELL 993
               :...||.|:|..:....: :|..|..::.:||:|||||.:.::|:|
pombe   910 EPKSEAVTSNNAALNTGDHPVSIKHAINIKFHDGFSNAVRKPISLNEIL 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cutlet	NP_787969.1	PRK04195	416..>645	CDD:235250	89/241 (37%)
ctf18	NP_595200.1	PRK04195	353..>618	CDD:235250	108/305 (35%)